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by Norgine
with support from earthware

Summary of work

In Europe, 200,000 people are affected by Hepatic encephalopathy (HE) – a potentially fatal decline in brain function as a result of liver disease.  HE is preventable and treatable, yet poorly diagnosed as many patients and carers are unaware of the signs and symptoms of the disease.

LiverSync® is a free, software-based, class 1 medical device (under Medical Device Directives, or MDD) developed by Norgine and earthware. It is designed to help liver disease patients living with liver cirrhosis who have had, or are at high risk of developing, HE.

Using a range of short cognitive tests that patients can complete anytime, anywhere, the LiverSync® app monitors trends in brain function and memory that may be affected by advanced liver disease. Patients can share information from the app with carers and healthcare professionals, helping them to get a diagnosis and treatment as early as possible.

Delivered in four languages, in a time frame of just ten months, LiverSync® is the first, comprehensive patient app and HCP web platform that allows patients, carers and HCPs to test and track patients’ cognition in real time and over time, to allow rapid interventions and active management of HE symptoms as they develop.

Judges' comments

The judges enjoyed this entry and the app. Norgine and earthware did really well to develop it in such a short period of time and it is a great tool for patients to identify with and was very ambitious launching in several countries.


KnowHAE – Improving Understanding in Hereditary Angioedema - by Takeda UK
with support from Makara Health

Highly commended


Why Sit it Out? - by CSL Behring
with support from Pegasus

Face Up to Rosacea - by Galderma
with support from Havas Life Medicom

LiverSync® - by Norgine
with support from earthware

Key dates

Entry deadline 26 August 2021
Extended entry deadline 2 September 2021*
*additional fee applies
Judging Day 1 October 2021
Company of the Year Interviews 22 October 2021
PMEA Event 24 November 2021