Please login to the form below

Not currently logged in
Email:
Password:

Amgen and Takeda lung drug fails trial

Amgen and Takeda have revealed that its lung cancer drug motesanib has failed to meet its endpoint in a phase III trial
Amgen and Takeda have revealed that its lung cancer drug motesanib has failed to meet its endpoint in a phase III trial. 

The drug failed to demonstrate an improvement in overall survival rate when combined with paclitaxel and carboplatin in 1,090 patients with advanced non-squamous non-small cell lung cancer.

In this trial, as in earlier trials of motesanib, the patients who received the drug were also more likely to experience serious adverse events more frequently than those who were given a placebo. Among the adverse events reported were hypertension and bleeding disorders.

Roger M Perlmutter, executive vice president of research and development at Amgen, said: "We are disappointed with the results from this trial, but look forward to further analysis of the data which may ultimately help inform future research in this area."

No decision has been made about continuing development.

31st March 2011

Share

Related Hub content

    Your search did not contain any words. Please try again.

Featured jobs

Subscribe to our email news alerts

PMHub

Add my company
Cello Health Consulting

Impressive real world experience and expertise fused with process and fresh perspective to unlock opportunities for you, your brand and...

Latest intelligence

Business in the USA
The pharma business environment in the US
Tighter regulations, more pricing controls and increased international competition will drive market improvements...
babylon virtual health service
VIDEO: Switching to a virtual health service
Ali Parsa, CEO and founder of babylon, discusses the benefits of conducting healthcare consultations via a smartphone...
Online Physician Communities
Is the pharma industry bad?
Surveys of doctors and the public suggest not...