Please login to the form below

Not currently logged in
Email:
Password:

Boehringer’s Vargatef approved in the EU for lung cancer

Marks company’s second oncology drug to hit market
EU flag

Boehringer Ingelheim continued to build its oncology ambitions with European approval for a second lung cancer drug.

The European Commission granted marketing authorisation for Vargatef (nintedanib) in combination with docetaxal for use in adult patients with locally advanced, metastatic or locally recurrent non-small cell lung cancer (NSCLC) after first-line chemotherapy.

Prof Klaus Dugi, Boehringer's chief medical officer, said: “The approval of Vargatef expands our oncology portfolio, following last year's approval of Giotrif (afatinib) for another specific type of lung cancer.”

The launch of Giotrif/Gilotrif in 2013 as a treatment lung cancer patients who express epidermal growth factor receptor (EGFR) marked Boehringer's entry onto the oncology market.

The addition of Vargatef widens the potential patient base for the German company, allowing Boehringer to make sizeable inroads into lung cancer.

Vargatef, a triple angiokinase inhibitor, has impressed in clinical trials, including the LUME-Lung 1 clinical trial involving 1,314 patients with NSCLC.

The drug demonstrated that, compared to docetaxel alone, Vargatef extended median survival from 10.3 months to 12.6 months, with a 25.7% surviving for two years or more.

Nintedanib has also shown potential outside of cancer, recently being recommended for EU approval as a treatment for the rare lung condition idiopathic pulmonary fibrosis (IPF). The drug received US approval in this indication in October under the name Ofev.

Article by
Kirstie Pickering

28th November 2014

From: Sales

Share

Tags

Featured jobs

Subscribe to our email news alerts

PMHub

Add my company
SEVEN STONES

Seven Stones is a creative, independent healthcare communications agency of movers and thinkers. We've been doing health differently since 1991....

Latest intelligence

The gene therapy revolution
Gene therapies are bringing new hope for many people with diseases caused by genetic disorders...
PM Society Digital Awards – the power of together
Our chief executive, Emma Statham, writes about the value of awards and the power of together....
Seduction_feature_image_thumb.jpg
Seduce anyone in four simple steps
You know the health of the global economy is dependent on our ability to seduce one another – don’t you? And you know that we need to be able to...

Infographics