Please login to the form below

Not currently logged in

EC approval halves blood cancer relapse

Targeted cancer therapy MabThera (rituximab) approved in the UK as an extended first-line treatment for follicular lymphoma
The European Commission (EC) has approved the extended use of Roche's targeted antibody MetaThera (rituximab) as "maintenance treatment"for people with follicular lymphoma (FL) who have responded to induction therapy. 
The EC's decision in favour of rituximab as first line maintenance treatment significantly expands the treatment options available to existing patients and offers newly-diagnosed patients an active treatment strategy. Prior to rituximab's approval, patients had to adopt a "watch and wait" approach. 
FL is marked by multiple relapses and progressively shorter periods of remission that are harder to achieve
By giving rituximab alone as maintenance therapy for two years following induction with immunochemotherapy, the risk of relapse after two years is halved, compared to stopping active treatment after initial induction therapy. Extended use of rituximab also reduces the likelihood of further chemotherapy without significantly impacting quality of life for two years by keeping the cancer at bay. 
The EC's approval was based on results from the phase III PRIMA trial, the largest ever trial investigating FL.

23rd November 2010


Featured jobs

Subscribe to our email news alerts


Add my company
Virgo Health

Virgo Health is an award-winning global healthcare communications and medical education agency comprising specialists with some of the best skills,...

Latest intelligence

Navigating the antibiotic resistance crisis
Blue Latitude Health speaks to Tara DeBoer, PhD, Postdoctoral Researcher and CEO of BioAmp Diagnostics to explore the antimicrobial resistance crisis, and learn how a simple tool could support physicians...
Combined immunotherapies – potential and pitfalls
‘Combining therapeutic compounds is the first logical step towards better results, namely higher rates of patients responding to treatment, with deeper and more sustained responses’...
Report: Achieving launch excellence in the challenging healthcare markets of today
Our in-depth report is based on original data and expert interviews, which coupled with our own experience, ensures we give you the best recommendations for achieving launch success in challenging...