Please login to the form below

Not currently logged in
Email:
Password:

HIV link to smallpox hypothesised

The spread of HIV may be linked to the eradication of smallpox 30 years ago, according to a study published in the journal BMC Immunology

The exponential spread of HIV infection may be linked to the eradication of smallpox 30 years ago, as immunisation with vaccinia, the vaccine used against smallpox, may also have provided protection against the HIV virus, according to a study published in the journal BMC Immunology.

The study authors claim that the behaviour of the HIV pandemic is insufficiently explained by the currently proposed theories, including contamination of polio vaccine and the reuse of unsterilised equipment, but that the rise of HIV infection coincides with the eradication of smallpox. The researchers therefore compared HIV-1 susceptibility in peripheral blood mononuclear cells in vaccinia vaccine-immunised patients with vaccine-naïve patients.

Cells of subjects who had received the vaccinia virus in the preceding 3–6 months were up to five times less likely to demonstrate replication of the HIV virus, compared with cells from unvaccinated subjects. Adding autologous serum increased HIV replication in unvaccinated subjects, but not in vaccinated subjects.

The authors concluded that prior immunisation with the vaccinia vaccine may provide some degree of protection against HIV infection or progression, though further studies need to be conducted before the vaccine is recommended for fighting HIV.

24th May 2010

Share

Featured jobs

Subscribe to our email news alerts

PMHub

Add my company
Swordfish Advertising

At Swordfish Advertising, we believe building an effective brand shouldn't be stressful. Don't get us wrong; it takes blood, sweat...

Latest intelligence

PM Society Digital Awards – the power of together
Our chief executive, Emma Statham, writes about the value of awards and the power of together....
Seduction_feature_image_thumb.jpg
Seduce anyone in four simple steps
You know the health of the global economy is dependent on our ability to seduce one another – don’t you? And you know that we need to be able to...
What Would Jeremy Do? : Assessing the impact of a Corbyn-led Labour government
GK Strategy are delighted to announce the launch our latest briefing paper entitled ‘What Would Jeremy Do? Assessing the impact of a Corbyn-led Labour government’....

Infographics