Please login to the form below

Not currently logged in
Email:
Password:

NICE approves RoActemra and MTX for RA

NICE has approved RoActemra plus methotrexate for use in rheumatoid patients who have failed or cannot take MabThera

The National Institute for Health and Clinical Excellence (NICE) has approved RoActemra (tocilizumab) plus methotrexate (MTX) for use in rheumatoid arthritis (RA) patients who have failed or cannot take MabThera (rituximab).

In clinical trials, RoActemra given with MTX achieved clinical remission rates almost six times higher than MTX alone and halted joint damage in 85 per cent of people compared to just 67 per cent treated with MTX alone, at 52 weeks.

The decision fails to give healthcare practitioners full choice to use the therapy earlier, as per its licence and usage in most of Europe and Scotland. Roche and Chugai are seeking to make RoActemra more widely available and are working within the NICE process to facilitate this.

Professor of rheumatolgy Paul Emery at the University of Leeds said: "This decision is very good news for the many patients who will benefit now and in the future. Although we would love the freedom to use this drug in all its licensed indications, as in Scotland the turnaround from NICE is encouraging as it shows that RA is being recognised as a serious but treatable condition."

There are around 646,000 people in the UK with RA – an incurable, painful and debilitating auto-immune disease where the body attacks itself, most noticeably in the joints. One third of those adults affected stop working within two years of onset and around half are unable to work through disability within 10 years.

31st August 2010

From: Healthcare

Share

Featured jobs

Subscribe to our email news alerts

PMHub

Add my company
Apex.co.uk Conferences, Events and Exhibition Stands

Apex.co.uk is one of the UK’s leading event and exhibition agencies, specialising in healthcare. We understand your communication goals, whether...

Latest intelligence

Can we talk about the ego-bias and chemicals influencing your target audience’s behaviour?
Over the Summer, the Page & Page team became fascinated by two books on this very subject. Two books from one author, Dean Burnett, an eminent neuroscientist, lecturing at Cardiff...
Paris
Making Europe a leader in bioscience: boosting trust and opening minds
A vision of Paris as Europe’s leading hub for life sciences innovation...
Ali Frederic Ben-Amor
Tackling a formidable foe
Ali Frederic Ben-Amor tells how Merck is taking the fight to multiple sclerosis...

Infographics