Please login to the form below

Not currently logged in
Email:
Password:

NICE in U-turn on Novartis’ Lucentis in diabetic macular oedema

Patient access scheme influences draft recommendation

National Institute for Health and Clinical Excellence (NICE)

Novartis' Lucentis could be available for mainstream use in the NHS to treat visual impairment due to diabetic macular oedema (VI-DMO) after the National Institute for Health and Clinical Excellence (NICE) issued a draft recommendation overturning a previous negative decision made last year.

The revised guidance, which only applies to patients who have a central retinal thickness of 400 micrometres or more, is due to a patient access scheme implemented by Novartis.

This means the pharma company would cover part of the drug's cost of £742.17 per monthly injection when used to treat the condition, although exactly how much was not disclosed.

In addition, NICE's draft recommendation was also influenced by further data provided by Novartis about the drug's benefits in the specific group of patients it is now provisionally recommended for.

“The manufacturer included updated analyses showing that ranibizumab could be expected to have a superior relative effect among people with central retinal thickness greater than 400 micrometres,” said Professor Carole Longson, Health Technology Evaluation Centre Director at NICE.

In a statement, Novartis said it was “pleased” with NICE's latest guidance, although expressed disappointment it didn't apply to patients with retinal thickness less than 400 micrometres.

The company said: “Novartis however remains concerned that limiting ranibizumab to those with a retinal thickness of 400 micrometres or more will result in patients with high unmet need, who do not meet the criteria, not gaining access.”

Lucentis is currently the only licensed anti-vascular endothelial growth factor (VEGF) treatment for VI-DMO.

If made available on the NHS, it would provide an alternative to laser treatment for patients with VI-DMO is laser treatment, which is unsuitable for certain patients and is not generally associated with improvements in vision.

There now follows a consultation period, with final guidance is expected in February 2013.

5th October 2012

From: Sales

Share

Tags

Featured jobs

Subscribe to our email news alerts

PMHub

Add my company
Kantar Health

Kantar Health is a leading global healthcare consulting firm and trusted advisor to many of the world’s leading pharmaceutical, biotech,...

Latest intelligence

If you needed an organ transplant, would you have one?
Lauren Packer discusses the worsening problem in the UK with an imbalance between the number of organs needed, and the number of those being donated....
Why tugging at our heartstrings is no longer enough to make us open our purses
Charlotte Shyllon (Director and Partner) and Maren Thurow (Senior Account Executive), discuss the highly emotive Make a Child Cry campaign video from Doctors of the World (Médecins du Monde)....
quantify_messages.png
Exploring full potential of e-detailing data
Today’s high quality e-detailing data can create better quality conversations with healthcare professionals and result in improved access and relationships....

Infographics