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Positive opinion for Allergan's NDO treatment

A positive opinion is given from the Irish Medicines Board for BOTOX treatment for neurogenic detrusor overactivity (NDO)

Allergan's BOTOX has received a positive opinion from the Irish Medicines Board, for the use of BOTOX for the management of urinary incontinence in adults with neurogenic detrusor overactivity (NDO).

NDO results from neurogenic bladder, due to stable sub-cervical spinal cord injury (SCI) or multiple sclerosis (MS). NDO results in involuntary contractions of the detrusor muscle within the bladder during its filling stage. This over activity often leads to urinary incontinence.

It has been shown that targeted injections of BOTOX into the bladder muscle can reduce the involuntary contractions and increase bladder capacity, therefore reducing the number of urinary leaks.

Gaining this opinion is considered to be an important step towards securing national licences in the 14 European countries involved in the Mutual Recognition Procedure.

9th August 2011

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