Please login to the form below

Six factors that drive a multiple sclerosis patient's choice of disease-modifying therapy

MS advocate Trishna Bharadia explains the numerous factors that lead patients to choose a disease-modifying therapy, including the important considerations healthcare professionals and pharma often forget.

MS advocate Trishna Bharadia explains the numerous factors that lead patients to choose a disease-modifying therapy, including the important considerations healthcare professionals and pharma often forget​.

When I was diagnosed with relapsing multiple sclerosis (RMS) in 2008, the landscape for disease-modifying therapies (DMTs) looked very different from now. There were five DMTs available on the NHS for RMS and nothing for people with progressive MS. At the start of 2019, options are very different. There are 14 DMTs available for people with RMS and some for people with progressive MS who still experience relapses. There is also optimism that soon DMTs will become widely available for people with progressive MS, evidenced by the current pipeline and the funding and attention being given to this area.

A misconception I often encounter from pharma is that choosing a DMT is black and white with the only considerations being efficacy and side effects. This isn’t true. With the landscape changing so rapidly, patients with MS face more choices and increasingly complex decisions about treatment. As a result, it’s important for clinicians, pharma and regulators to understand some of the factors that can influence decisions about whether to take a DMT (or not) and why one may be chosen over another.

With the landscape changing so rapidly, patients with MS face more choices and increasingly complex decisions about treatment. As a result, it's important for clinicians, pharma and regulators to understand some of the factors that can influence decisions about whether to take a DMT (or not) and why one may be chosen over another.

1. ELIGIBILITY AND AVAILABILITY

There are stricter criteria for some DMTs and some are more easily available in certain geographic areas, either due to funding or resources. For example, some hospitals have longer waiting lists for infusion drugs because they don’t have sufficient nurses or physical capacity to administer them. However, if a patient is willing and able, they might decide to travel further to get the DMT they want.

2. EFFICACY

Efficacy is an obvious influencing factor. However, the way that patients’ view this can sometimes differ from the way clinicians’, pharma and regulators’ view it. The 2017 ‘Missing Pieces report’ by Sanofi showed 65% of people with MS valued maintaining independence and described it as their main treatment goal, with reducing relapses coming second to that. In addition, 54% said they were worried and 45% said they were scared of possibly becoming disabled, indicating that quality of life is a key outcome measure for patients. Despite this, the report also showed that just half of those surveyed said disability was discussed with their HCP at diagnosis.

DOWNLOAD THE FULL ARTICLE HERE

6th February 2019

Share

Tags

Company Details

Blue Latitude Health

+44 203 328 1840

Contact Website

Address:
Blue Latitude Health (UK)
140 Aldersgate Street
London
EC1A 4HY
United Kingdom

Latest content on this profile

Report: Customer experience, shaping digital healthcare
In this issue of ‘Perspective’ we speak with industry experts to learn about the world of digital healthcare, and how pharma is beginning to utilise these modern technologies to enhance treatment and improve patient and stakeholder outcomes.
Blue Latitude Health
The changing face of pharma in the precision era
Blue Latitude Health speaks to Nancy Brandt, a Senior Leader in Global Medical Information at a top 20 biopharma organisation. Here, she reveals what pharmaceutical companies need to do to prepare to bring precision medicines to market and how she is ensuring the patient is consulted every step of the way.
Blue Latitude Health
Creative problem solving, solved
Customer Experience Consultant Eimear Power explains how pharma teams can unlock their creativity and foster truly innovative ideas.
Blue Latitude Health
Three strategies for managing loss of exclusivity successfully
Claire Taylor, Senior Associate Consultant at Blue Latitude Health explains why you should be strategically planning your LOE strategy years in advance.
Blue Latitude Health
Empowered patients: shaking the foundations of healthcare
Precision medicine represents a new paradigm in healthcare.This new approach to treating and preventing disease views the patient holistically, analysing their genes, environment and lifestyle, and using this information to make a more accurate treatment decision. Here we discuss the barriers, opportunities and potential outcomes of the precision medicine era in healthcare.
Blue Latitude Health
A uniquely English genomic medicine service
The UK National Health Service is developing one standardised approach to embedding precision medicine across the whole of England. Blue Latitude Health speaks to Dr Tom Fowler, Deputy Chief Scientist and Director of Public Health at Genomics England, to find out how the NHS is achieving this goal.
Blue Latitude Health