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Actos

This page shows the latest Actos news and features for those working in and with pharma, biotech and healthcare.

Takeda and Zinfandel abandon Alzheimer’s drug

Piogliazone is sold by Takeda under the Actos brand and was a $4bn-a-year product before losing patent protection in 2011, after which generic versions entered the market.

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NICE backs freer use of SGLT2 inhibitors for diabetes

The new guidance allows the drugs to be used first-line for people who cannot tolerate metformin, and in whom sulfonylureas or Takeda's Actos (pioglitazone) are not considered appropriate.
Takeda to pay $2.4bn to settle Actos cancer suits

Actos (pioglitazone) is licensed to help patients with type II diabetes reduce their sugar levels and has been on the market for more than 15 years. ... Actos has generated more than $16bn in sales since its 1999 release, according to court filings, but
US judge cuts billions from Takeda/Lilly Actos payment

The case is one of thousands consolidated in US courts that claim Takeda and Lilly deliberately misled regulators about a link between type 2 diabetes drug Actos and bladder cancer. ... Takeda has set up six trials involving Actos to help support the drug
Takeda loses in lawsuit claiming cancer link to Actos

Actos was a huge commercial success for Takeda, with sales peaking at $4.5bn before losing patent protection in the US in 2012. ... Court documents obtained by Bloomberg suggest Actos has generated more than $16bn in sales since its US launch in 1999.
Takeda: No link between Actos and bladder cancer

Concerns were raised several years ago about Actos' potential to increase the risk of bladder cancer, leading to the withdrawal of the drug in France and Germany and the launch of ... statistically significant increased risk of developing bladder cancer

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Interview: Trevor Smith, Takeda

Ulcer drug lansoprazole and prostate cancer treatment leuprorelin already faced generic competition and before the deal was completed Takeda's diabetes drug Actos (pioglitazone) lost exclusivity in January 2011. ... German authorities quickly followed
Country report: The healthcare market in Japan

to its multi-billion dollar main product, the antidiabetic Actos (pioglitazone), in August. ... Actos was withdrawn from the market in Germany and France, but not in the US.

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