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adaptive trial design

This page shows the latest adaptive trial design news and features for those working in and with pharma, biotech and healthcare.

WHO takes stock of global COVID-19 R&D progress

WHO takes stock of global COVID-19 R&D progress

There were also some associated safety signals in clinical laboratory findings of the add-on Discovery trial associated with each drug. ... That included taking a look at the use of global, multi country, adaptive trial design with a common data safety

Latest news

  • Trials of NewLink's Ebola vaccine 'imminent' Trials of NewLink's Ebola vaccine 'imminent'

    The experts noted that while a conventional randomised controlled trial would be the preferred option, it may be possible to consider alternative designs such as the "randomised stepped wedge" model. ... This is an adaptive trial design that draws on

  • Adapt and overcome: Adaptive trial design in research Adapt and overcome: Adaptive trial design in research

    The pharma industry is slowly starting to embrace adaptive trial design, though not as quickly as once hoped, thanks largely to regulatory uncertainty. ... A survey carried out byhas found that while many drug companies are anticipating the use of an

  • Never-ending story: modernising clinical trial design

    Berry is one of the principal investigators in a new trial which arguably takes the adaptive trial design concept to a new height. ... Berry hopes I-SPY 2 will serve as a showcase for the power of adaptive trial design, and continue to encourage the

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Latest Intelligence

  • Brain power: fresh approaches to Alzheimer’s drug discovery Brain power: fresh approaches to Alzheimer’s drug discovery

    competitive data, trial recruitment problems, and trial design that is ill-suited to making rapid progress against this elusive disease. ... The EPAD platform will allow new therapies to be tested in a streamlined way, using adaptive trial design to test

  • Immunotherapy combination trials Q&A Immunotherapy combination trials Q&A

    There has been a rapid evolution in clinical trial design in IO, eg basket trials, adaptive trials, etc. ... CL: Evolution of trial design has benefited greatly in past decades, as the search for meaningful signals in patients has provided faster

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Latest from PMHub

  • A forward march for adaptive designs

    From new methodology to IND submission priority to portfolio impact, adaptive trial design continues to make headway in the US and Europe. ... Adaptive trial design continues to make headway with both the FDA and EMA recognising the benefits that this

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