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ADC

This page shows the latest ADC news and features for those working in and with pharma, biotech and healthcare.

Seattle Genetics claims key US approval for Adcetris

Seattle Genetics claims key US approval for Adcetris

The approval is also important for Seattle after its aborted $2bn deal to license Immunomedics’IMMU-132, another ADC drug for triple-negative breast cancer (TNBC), which was scuppered by a

Latest news

  • Takeda bags EU approval for Adcetris in lymphoma Takeda bags EU approval for Adcetris in lymphoma

    CTCL). Adcetris (brentuximab vedotin) - a CD30-targeting antibody drug conjugate (ADC) - already has conditional approval in the EU for certain adult patients with relapsed or refractory CD30-positive Hodgkin lymphoma, but

  • Seattle Genetics' Adcetris earns FDA priority review status Seattle Genetics' Adcetris earns FDA priority review status

    Data from the trial - which evaluated a combination of Adcetris plus Adriamycin, vinblastine, dacarbazine (ADC) - showed a 23% reduction in the risk of progression, death or need for additional therapy, achieving

  • Axovant joins ever-growing Alzheimer’s failure club Axovant joins ever-growing Alzheimer’s failure club

    In a statement, New York-based Axovant said intepirdine did not improve symptoms compared to placebo on two widely-used AD symptom measures - the ADAS-Cog and ADCS-ADL scales - promoting

  • FDA clears Pfizer's leukaemia drug Besponsa FDA clears Pfizer's leukaemia drug Besponsa

    FDA clears Pfizer's leukaemia drug Besponsa. The breakthrough treatment is the first CD22-targeted ADC to be approved in the US. ... It is the first CD22-targeted ADC to be approved for marketing in the US, according to Pfizer.

  • Celgene steps back from $1bn Sutro acquisition Celgene steps back from $1bn Sutro acquisition

    Now Celgene has decided to focus its involvement on four programmes headed to clinical trials - including an antibody-drug conjugate (ADC) targeting B-cell maturation antigen (BCMA). ... 001 and STR0-002, an ADC which targets folate receptor alpha for

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Latest Intelligence

  • Deal Watch February 2017 Deal Watch February 2017

    Competitive deal tendering and investor revolt. One of the largest therapeutic deals in February was the Immunomedics licence with Seattle Genetics for a phase 2 stage antibody drug conjugate (ADC), sacituzumab ... As an ADC IMMU-132 contains SN-38,

  • Deal Watch January 2017 Deal Watch January 2017

    465. Abzena. Not disclosed. Licence. ThioBridge ADC linker technology. 300. Domain Therapeutics.

  • Deal Watch February 2016 Deal Watch February 2016

    Mersana could receive an additional $750m in milestones if the XMT-1522 and ADC programmes are successful, plus sales royalties. ... acquisition - company. 895. Mersana Therapeutics/ Takeda. XMT-1522, Fleximer-based ADC therapy targeting HER2-expressing

  • Deal Watch January 2016 Deal Watch January 2016

    Abzena/(Partner nd). Licence . Novel site specific ThioBridge antibody drug conjugate (ADC) linker technology.

  • Pharma deals in August 2015 Pharma deals in August 2015

    Late to join the immuno-oncology race, ADC 1013 is a CD40 targeting antibody in phase I clinical studies; J&J assumes development responsibilities when the phase I studies are completed. ... Licence. 727. Alligator Bioscience. J&J. ADC 1013 in solid

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Approximately 0 fully matching, plus 17 partially matching documents found.

Latest appointments

  • Glythera strengthens its scientific advisory board and appoints CSO Glythera strengthens its scientific advisory board and appoints CSO

    Dr Lutz was previously vice president of translation research and development at ImmunoGen, where he was responsible for all early-stage ADC development programmes. ... Dr Dave Simpson, chief executive officer of Glythera, said: “Robert Lutz’s

  • Glythera appoints Dr Mike Owen Glythera appoints Dr Mike Owen

    His experience in advancing scientific discoveries from the lab to commercialisation will be invaluable in helping us fully exploit our unique ADC platform, both in the development of our proprietary product

  • ADC Therapeutics expands team ADC Therapeutics expands team

    ADC Therapeutics has significantly expanded its team head of putting its first antibody drug conjugates (ADCs) into clinical development. ... Michael Forer, CEO of ADC Therapeutics, said: “ The quality of individuals and depth of experience that we

  • ImmunoGen hires VP product strategy ImmunoGen hires VP product strategy

    These programmes focus on antibody-drug conjugates (ADCs) to target cancers. The most successful of these ADCs so far is Kadcyla, which ImmunoGen developed with Genentech, now a part of Roche.

  • CytomX makes senior changes following Pfizer deal CytomX makes senior changes following Pfizer deal

    conjugates (ADCs) for cancer.

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Approximately 1 fully matching, plus 4 partially matching documents found.

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