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BCMA-targeting therapy

This page shows the latest BCMA-targeting therapy news and features for those working in and with pharma, biotech and healthcare.

GSK preps filings for BCMA-targeting multiple myeloma drug

GSK preps filings for BCMA-targeting multiple myeloma drug

GSK2857916 is one of a slew of BCMA-targeting therapies coming through the biopharma industry pipeline, jostling for position with a CAR-T therapy from Celgene and Bluebird Bio called bb2121 ... It is the most advanced BCMA-targeting ADC in development,

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  • Europe urged to adapt faster to gene therapy challenges Europe urged to adapt faster to gene therapy challenges

    Meanwhile Bluebird is proposing a similar five-year instalment plan for its 1.57m beta thalassemia therapy Zynteglo. ... The next therapy area which could be transformed by cell therapy is multiple myeloma, where BCMA-targeting CAR-T therapies are in the

  • Bluebird’s myeloma CAR-T safety ‘could support outpatient use’ Bluebird’s myeloma CAR-T safety ‘could support outpatient use’

    Expects to file with the FDA next year. Bluebird Bio and partner Celgene have published data for their BCMA-targeting cell therapy bb2121 for multiple myeloma, reinforcing its position as the ... The two partners will have to move fast to stay ahead of a

  • Gilead adds to CAR-T assets with Cell Design Labs buyout Gilead adds to CAR-T assets with Cell Design Labs buyout

    One CDL approach - called synNotch - is designed to require two antigens rather than one to active the CAR-T cell, potentially making the therapy more tumour-specific. ... The acquisition was announced just before the American Society of Haematology (ASH)

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