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betrixaban

This page shows the latest betrixaban news and features for those working in and with pharma, biotech and healthcare.

CHMP turns down BMS’ Opdivo/Yervoy for kidney cancer

CHMP turns down BMS’ Opdivo/Yervoy for kidney cancer

It also turned down two previously-rejected medicines – Portola’s factor Xa inhibitor anticoagulant Dexxience (betrixaban) and Radius International’s osteoporosis candidate Eladynos (abaloparatide) – for the second time after a

Latest news

  • CHMP backs first-line use for AZ’s Tagrisso in lung cancer CHMP backs first-line use for AZ’s Tagrisso in lung cancer

    The three drugs in question are Portola’s anticagulant Dexxience (betrixaban), Radius’osteoporosis candidate Eladynos (abaloparatide) and AB Science’s Alsitek (masitinib), filed for neurodegenerative disease amyotrophic lateral sclerosis (ALS).

  • ViiV’s two-drug HIV combo backed by CHMP ViiV’s two-drug HIV combo backed by CHMP

    There was bad news for three other companies, with the CHMP issuing negative opinions for Portola’s Dexxience (betrixaban) for the prevention of venous thromboembolism, Radius International’s osteoporosis candidate Eladynos

  • Bad news for Portola as CHMP considers Factor Xa drugs Bad news for Portola as CHMP considers Factor Xa drugs

    Bad news for Portola as CHMP considers Factor Xa drugs. The committee are ‘unlikely’to adopt a positive opinion for betrixaban. ... for betrixaban, its oral, once-daily Factor Xa inhibitor, as well as antidote drug andexanet alfa.

  • Archive listing

    The committee are ‘unlikely’to adopt a positive opinion for betrixaban. .

  • Merck collaborate over betrixaban

    In return for an exclusive worldwide license to betrixaban, Merck will pay Portola an initial fee of $50m. ... for additional royalties and to co-promote betrixaban with Merck in the US.

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Latest Intelligence

  • Modern anticoagulants threaten status quo Modern anticoagulants threaten status quo

    Betrixaban. Betrixaban (Portola Pharmaceuticals) is a long-acting oral factor Xa inhibitor that entered phase III trial development for VTE prevention in medically ill patients in March 2012. ... Promising phase II results of betrixaban for VTE

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