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CAR-T

This page shows the latest CAR-T news and features for those working in and with pharma, biotech and healthcare.

FDA delays BMS’ liso-cel decision, citing COVID-19 travel restrictions

FDA delays BMS’ liso-cel decision, citing COVID-19 travel restrictions

Inspection of third-party manufacturing plant delayed due to COVID-19. The US Food and Drug Administration (FDA) has delayed a crucial decision for Bristol Myers Squibb’s CAR-T therapy ... BMS also agreed similar conditional payments, dependent on

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  • Surviving cancer: a new era for patients Surviving cancer: a new era for patients

    Chimeric antigen receptor T-cell therapy. Chimeric antigen receptor (CAR) T-cell therapy consists of engineering receptors in the body that selectively interact with cancer cells, inducing cell death without affecting ... CAR-T therapy has potential

  • The impact of COVID-19 on clinical trials The impact of COVID-19 on clinical trials

    Therapy mechanism of action – immunosuppressive therapies and therapies that require complex and prolonged hospital visits (eg, CAR-T and gene therapies).

  • COVID-19: the race to find a vaccine COVID-19: the race to find a vaccine

    The interleukin-6 receptor antagonist is approved for use in indications including the management of cytokine release syndrome in CAR-T patients.

  • Cortellis Drugs to Watch in 2020 report Cortellis Drugs to Watch in 2020 report

    Thanks to the CAR construct, the engineered T cells can recognise and attack the CD19-expressing cancer cells. ... This composition could confer efficacy and safety advantages, including fewer adverse effects such as cytokine release syndrome (CRS) and

  • China’s homecoming heroes fuel a biotech boom with rapid CAR-T advances China’s homecoming heroes fuel a biotech boom with rapid CAR-T advances

    At the spear point is China’s emergence as the epicentre of biotech research and development, with its performance on CAR-T therapies turning heads. ... It now has more than 300 CAR-T clinical trials underway and collaboration with European and

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