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cilastatin

This page shows the latest cilastatin news and features for those working in and with pharma, biotech and healthcare.

Merck preps regulatory filings for much-needed antibiotic combo

Merck preps regulatory filings for much-needed antibiotic combo

The regimen combines Merck’s imipenem/cilastatin duo - sold as Primaxin as a broad-spectrum antibiotic for decades - with a new beta lactamase inhibitor called relebactam that is designed to restore ... The pivotal phase III trial showed that

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  • Merck starts pivotal trials of new antibiotic combination Merck starts pivotal trials of new antibiotic combination

    plus cilastatin, another drug designed to tackle resistance. ... The trial showed adding relebactam treatment to imipenem/cilastatin was not inferior to imipenem/cilastatin plus placebo - an important initial finding which shows the beta lactamase

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