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clinical trials

This page shows the latest clinical trials news and features for those working in and with pharma, biotech and healthcare.

Latest news

  • Duchenne UK backs Evox dystrophin delivery project Duchenne UK backs Evox dystrophin delivery project

    as well as experimental gene therapies that try to deliver a working dystrophin gene that are in clinical trials and gene-editing approaches such as CRISP/Cas9 that attempt to correct

  • Entering the era of digital trials Entering the era of digital trials

    decades. Clinical trials performed before and after the adoption of electronic data capture (EDC) were the same in many key respects. ... Still bigger breakthroughs may come from technologies applied to the conduct of clinical trials.

  • MedCity sets up advanced therapy research network MedCity sets up advanced therapy research network

    London, Oxford and Cambridge, with speakers noting that the UK is a leader in ATMP clinical trials, recruiting more patients into studies than top US specialist centres such as Harvard and

  • The Final Frontier The Final Frontier

    What they really mean is that there’s no evidence for the use of medical cannabis in the way they would like to see the evidence: randomised- controlled trials, double-blind ... That is true. But it’s hard to conduct clinical trials on a therapeutic

  • Digital Trials Digital Trials

    The recent Clinical Trials Transformation Initiative (CTTI) report recommended that a short feasibility study is carried out prior to implementation of the technology in a large study. ... As a consequence, clinical trials are changing. Digital

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Latest Intelligence

  • Key considerations for disease- modifying Parkinson’s disease trials Key considerations for disease- modifying Parkinson’s disease trials

    Do not rely on biomarkers (such as pathological forms of α-Synuclein), but put clinical outcomes as an endpoint in phase 2 trials. ... Taking all these lessons learned into consideration should markedly lower the risk of a false negative result in

  • Alnylam’s big moment: bringing groundbreaking RNAi drugs to Europe Alnylam’s big moment: bringing groundbreaking RNAi drugs to Europe

    major advance in severe disease, despite some major bumps in the clinical development road and when big pharma companies got cold feet – and then finally proving its value to patients and ... and sustainable clinical pipeline and a robust product

  • Retaining reader value in plain language summaries of clinical studies Retaining reader value in plain language summaries of clinical studies

    From 2019, sponsors of clinical research will need to prepare plain-language summaries (PLSs) for all phase 1-4 interventional trials, to fulfil requirements for greater transparency under EU Clinical Trials ... Practice makes perfect. For now, summaries

  • Tackling a formidable foe Tackling a formidable foe

    Its trials demonstrated that patients achieved 50% fewer relapses and fewer new areas of MS activity and it currently has market authorisation in 39 countries. ... Working together. Hundreds of trials are bustling through clinical lines to decode the

  • Stakeholder dialogue in Europe’s adaptive pathways pilot Stakeholder dialogue in Europe’s adaptive pathways pilot

    Evidence suggests that medicines using the resulting accelerated access initiatives experience variable reimbursement outcomes due to uncertainties in the clinical or economic evidence base. ... Efficacy and safety data from early compassionate use

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