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clinical trials

This page shows the latest clinical trials news and features for those working in and with pharma, biotech and healthcare.

US announces $3bn funding boost for antiviral COVID-19 treatments

As part of this plan, the NIH will evaluate, prioritise and advance antiviral treatment candidates to phase 2 clinical trials. ... It will provide over $300m for research and lab support for potential treatments, as well as nearly $1bn for preclinical

Latest news

Biogen doses first patient in phase 3 systemic lupus erythematosus study

Additionally, we are reinforcing Biogen’s commitment to the inclusion of underrepresented groups in our clinical trials. ... This candidate began a phase 3 clinical trial in 2020 and targets the CD40L ligand, rather than the BDCA2 receptor.
Biogen to begin shipping newly approved Alzheimer’s treatment in two weeks

The sites include clinical trial centres, where the treatment will be given to patients who have been tested for amyloids, as well as additional sites that have the appropriate equipment to ... This included David Knopman, a neurologist at the Mayo
Novartis' Kisqali shows long-term improvements in breast cancer patients

Successfully demonstrating overall survival improvements in an incurable disease like metastatic breast cancer is a significant achievement, and is what we ultimately strive for in most clinical trials,” said Dennis Slamon, ... director of
Sinovac’s COVID-19 vaccine receives WHO emergency use listing

In clinical trials, the Sinovac vaccine was found to be 51% effective in preventing symptomatic disease, meeting the WHO's recommendation of at least 50% efficacy. ... Even though the clinical trials of CoronaVac enrolled few older adults aged over 60,
MorphoSys expands oncology pipeline with $1.7bn acquisition of Constellation Pharmaceuticals

Both product candidates are in mid- to late-stage clinical trials, with ‘broad therapeutic potential’ across various haematological and solid tumours. ... Pelabresib, a potentially first-in-class BET inhibitor, is currently being evaluated in phase 3

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Latest Intelligence

Patient diversity in clinical trials needs to be centre stage

lack of diversity in clinical trials by building evidence and amplifying patient voices. ... clinical trials through to understanding practical elements such as family commitments and compensation.
Your clinical trial participants are precious, so treat them as such

This last year with COVID-19 has clearly demonstrated that large numbers of healthy people can be recruited to clinical trials incredibly quickly. ... Additional burden may be financial, intellectual or practical. So how do we at Origins help to reduce
Diversity and inclusion in clinical trials

By Nuala Murphy. The inclusion of diverse patient populations in clinical trials is nothing new but the topic has risen to the surface in the last year and is now prevalent ... ways, the FDA guidance issued in November that addressed the multidimensional
Fair representation in research matters to the sector and to society

By Annette Jack. The majority of health research and clinical trials do not represent society. ... Community organisations can play a critical role improving representation in health research and trials.
Why we need to look beyond cultural competency to fix the patient diversity challenge

The lack of diversity in clinical research is a concerning issue, and the debate on how best to improve diversity in clinical trials is not a new one. ... Implicit bias can be found in clinical trials too, manifesting as a lack of diverse representation

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Latest appointments

NICE looks internally for new chief executive

Originally training in medicine, Leng went on to work on clinical trials and epidemiological research as well as a consultant in public health medicine. ... During her time at NICE, she held responsibility for setting up and running the clinical
New hires at Crescendo, Healx and Galecto

late phase clinical trials. Before that, he was clinical research physician at Chugai Pharma Europe, where he led clinical development for a bispecific T-cell engaging antibody programme and other early ... Prior to eTheRNA, Lindmark served as global VP
New hires at Bayer, Eisai and Accord Healthcare

She joins Eisai from Merck, where she served as executive director, clinical quality assurance, head of global GCP for infectious disease and vaccines. ... In that role, Chaturvedi oversaw the end-to-end quality assurance for a large portfolio of
New hires at Nanoform, Leo Pharma and Calliditas

and bringing products to market will play a key role as we progress development of Nefecon through phase 3 clinical trials”, said Renée Aguiar-Lucander, CEO of Calliditas Therapeutics.
Zelluna Immunotherapy appoints chief technology officer

His experience, acquired on both side’s of the Atlantic will provide invaluable for Zelluna in its immediate focus of delivering clinical proof of concept of its TCRs in adoptive cell ... He will play a big part in the execution of Zelluna’s

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Latest from PMHub

Why empathy in digital patient recruitment is vital

In this case, that’s getting patients to find out more about your clinical trial. ... The same applies to how they want to receive information. And of course, you have to consider diversity in clinical trials.
Live Webinar: Realizing the Potential of Genomics-Driven Precision Medicine

designing gene therapy trials, how to achieve true patient-centricity, and much more!
Why people join a clinical trial

To understand why people decide to take part in clinical trials, you first need to understand how people make decisions. ... In simple terms, we advertise clinical trials and attempt to get people to decide to take part.
Clinical trial design and how it can be used to improve the patient experience

For this article, we want to go back to basics and describe the main features of the most commonly used designs for clinical trials, why they are set-up in this ... Not all clinical trials are focused on new drugs. There are lots of trials that compare
Addressing the Gendered Health Data Gap

For example, women are 50% more likely to be misdiagnosed following a heart attack because participation in clinical trials is generally skewed towards males. ... This is also true of our healthcare systems; our clinical trials, our diagnostic approaches