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CNS

This page shows the latest CNS news and features for those working in and with pharma, biotech and healthcare.

Avanir’s week goes from bad to worse with Alzheimer’s stumble

Otsuka paid $3.5bn to acquire Avanir in 2014 as part of a strategy to expand its presence in the central nervous system (CNS) disease category in the US.

Latest news

J&J’s ponesimiod tops Aubagio in head-to-head MS trial

The company does however have a resurgent central nervous system (CNS) therapeutic category following the approval of Spravato(esketamine), a nasal spray for treatment-resistant depression that J&J reckons can
Boehringer tests speech as early warning for CNS diseases

Disordered speech is a common symptom of many central nervous system (CNS) disorders, but generally only becomes conspicuous once the disease is advanced, says Christoph Eschenfelder, who is running the Pathologic
AbbVie CEO Gonzalez defends Allergan takeover

For AbbVie, Allergan’s most interesting programmes are a clutch central nervous system (CNS) candidates including antidepressant Vraylar (cariprazine) – which it says has blockbuster potential – as well as oral CGRP inhibitors
Sanofi exiting Voyager gene therapy pact is ‘surprising’, says analyst

for CNS indications are in phase 3 trials in the eight major pharma markets (the US, France, Germany, Italy, Spain, the UK, Japan and China). ... non-CNS indications.
Stream on

your oncology, CNS and rheumatoid arthritis drugs.

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Latest Intelligence

China’s clinical trial shake-up

These reporting rules require sponsors to upload information such as endpoints and eligibility criteria to www.chinadrugtrials.org.cn.
Key considerations for disease- modifying Parkinson’s disease trials

By Dr Peter Schueler, Senior Vice President, Drug Development Services and Haichen Yang, Vice President, Global Therapeutic Lead, both at CNS, ICON plc.
Alnylam’s big moment: bringing groundbreaking RNAi drugs to Europe

The company is working on RNAi molecules which can work in CNS, something which would expand its therapeutic possibilities enormously, and hopes to have its first CNS-targetting candidate enter clinical
A quest for innovative solutions

PRISM has matured into an artery of new opportunities such as its collaboration on RADAR-CNS (Remote Assessment of Disease and Relapse - Central Nervous System), an initiative that aims to develop
The good, the bad and the ugly

Pfizer has large sales in CNS - $8.5bn in 2017. The majority come through Lyrica ($5bn). ... In Europe, a patent dispute over Lyrica became arguably the biggest CNS story in recent years.

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Latest appointments

Axovant poaches Allergan’s and Teva’s chief medical and science officers

development. “We have a wonderful opportunity to develop life-changing medicines for patients with CNS diseases.
Damien McDevitt moves from GSK to Acadia Pharmaceuticals

At Acadia, which focuses on the development and commercialisation of medicines for central nervous system (CNS) disorders, McDevitt will report to the company’s president and chief executive officer Steve Davis. ... This expertise, combined with his
Ron Menezes joins Almirall’s Aqua Pharmaceuticals

Menezes joins the group from Depomed Pharmaceuticals, where he served as vice president of sales and sales operations, pain and CNS.
emotive boosts its client services team

Joining as a senior account director, Andy Parry has 9 years’ experience in healthcare communications and has worked on global brands in CNS, infectious diseases, respiratory and rare disease.
Axon bolsters team with new PR Director hire

During her career, Smiddy has led local, regional and international programmes to support pharmaceutical products in numerous therapeutic fields including cardiology, immunology, CNS and oncology.

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Latest from PMHub

Diagnosing the lag in neuropsychiatric treatments

Unlike the other organs in our body, the central nervous system (CNS) is surrounded by the Blood Brain Barrier (BBB). ... To say the BBB presents a formidable challenge in CNS drug development is an understatement.
Innovative approaches in the treatment of multiple sclerosis

Multiple Sclerosis (MS) is a chronic autoimmune disease that affects the central nervous system (CNS), leading to progressive and permanent disability. ... In the central nervous system (CNS, which includes the brain, optic nerves and spinal cord),
Innovative approaches in the treatment of multiple sclerosis

Multiple Sclerosis (MS) is a chronic autoimmune disease that affects the central nervous system (CNS), leading to progressive and permanent disability. ... In the central nervous system (CNS, which includes the brain, optic nerves and spinal cord),
Shionogi Ltd. appoints Star for UK launch

Their pipeline focuses on infectious disease, pain, CNS and oncology. Star were chosen as preferred partner on the basis of the company’s ability to provide the very best talent to
A fast-growing client services team at emotive.

Starting his career in Medical Education and then moving into healthcare advertising, Andy has worked on large global brands in CNS, infectious diseases, respiratory and rare diseases. ... Also with a Biomedical Science degree, Sabrina worked in

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