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diffuse large B-cell lymphoma

This page shows the latest diffuse large B-cell lymphoma news and features for those working in and with pharma, biotech and healthcare.

Novartis follows Pfizer and freezes US prices this year

Novartis follows Pfizer and freezes US prices this year

for diffuse large B-cell lymphoma (DLBCL) and new migraine therapy Aimovig (erenumab).

Latest news

  • Another R&D flop for Incyte, but Jakafi keeps delivering Another R&D flop for Incyte, but Jakafi keeps delivering

    Meanwhile, Incyte was quick to point out that the failure of PI3K delta inhibitor INCB50465 in a form of NHL called diffuse large B cell lymphoma (DLBCL) does not affect phase ... II testing of the drug in other indications, including follicular lymphoma,

  • CAR-Ts Kymriah and Yescarta  step closer to approval  in Europe CAR-Ts Kymriah and Yescarta  step closer to approval  in Europe

    Unlike in the US, the drugs will go head-to-head straightaway, as Kymriah will be licensed for paediatric and young adult acute lymphoblastic leukaemia (ALL) ALL and adult diffuse large ... b cell lymphoma (DLBCL), the latter being the key battleground

  • The year of the blockbuster The year of the blockbuster

    These include Juno Therapeutics’CAR T-cell therapy, lisocabtagene maraleucel, for diffuse large B-cell lymphoma, and Alexion’s next-generation Soliris treatment, ravulizumab, for paroxysmal nocturnal haemoglobinuria.

  • New trial results suggest CAR-T effects are durable in lymphoma New trial results suggest CAR-T effects are durable in lymphoma

    Novartis has new data that it hopes can kickstart the take-up of its CAR-T Kymriah in its new B-cell lymphoma indication approved last month in the US. ... Updated results from the JULIET trial of the therapy in adults with relapsed or refractory diffuse

  • NHS chief pledges CAR-T support, but asks for pricing restraint NHS chief pledges CAR-T support, but asks for pricing restraint

    Kite’s CAR-T Yescarta (axicabtagene ciloleucel) was the first to be submitted for approval in Europe and is being reviewed by the EMA for diffuse large B-cell lymphoma (DLBCL), ... primary mediastinal B-cell lymphoma (PMBCL) and transformed follicular

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Latest Intelligence

  • Deal Watch January 2018

    The company switched focus to its JCAR017 programme and recently reported promising data in a pivotal trial for relapsed and/or refractory diffuse large B-cell lymphoma (DLBCL). ... DLBCL = diffuse large B-cell lymphoma. BTK = Bruton's Tyrosine Kinase.

  • Pharma deals in April 2015 Pharma deals in April 2015

    MEDI4736 is an immune checkpoint inhibitor which is targeted against programmed cell death (PD-L1). ... its SAR3419, an antibody-drug conjugate designed to treat diffuse large B-cell lymphoma (DLBCL) and other blood cancers.

  • Pharma deals during June 2014 Pharma deals during June 2014

    a deal with NanoString Technologies for the development of a companion diagnostic assay to support the development of Revlimid for treatment of Diffuse Large B-Cell Lymphoma at a more modest

  • Current development and marketing of biosimilar monoclonal antibodies in Latin America Current development and marketing of biosimilar monoclonal antibodies in Latin America

    NA. BC: Breast cancer; DLBCL: Diffuse large B-cell lymphoma; FL: Follycular Lymphoma; NA: Not applicable; NSCLC: Non-Small Cell Lung Cancer; RA: Rheumatoid Arthritis; TT: Technology transfer.

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Latest appointments

  • Celgene boosts CAR-T stake again with Bluebird Bio deal Celgene boosts CAR-T stake again with Bluebird Bio deal

    Celgene partnered with Bluebird on a portfolio of CAR-T candidates in 2013, and followed that up with a deal to zero in on B-cell maturation antigen (BCMA) two years ... That deal gave it rights to Juno’s lead CAR-T candidate JCAR017 (lisocabtagene

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