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DMD

This page shows the latest DMD news and features for those working in and with pharma, biotech and healthcare.

Duchenne UK backs Evox dystrophin delivery project

Duchenne UK backs Evox dystrophin delivery project

Oxford University spin-out Evox Therapeutics has won a £656, 000 ($858, 000) grant from a UK medical charity to test its large-molecule delivery technology in Duchenne muscular dystrophy (DMD). ... The funding round will help Evox carry out preclinical

Latest news

  • Entering the era of digital trials Entering the era of digital trials

    A version of the phenomenon affects trials in muscle disorders such as Duchenne muscular dystrophy (DMD). ... One study found kids with DMD walked 11% further if they were offered $50 (£39) to beat their previous distance.

  • Pfizer abandons antibody for Duchenne Pfizer abandons antibody for Duchenne

    Pfizer abandons antibody for Duchenne. Pfizer has halted development of its Duchenne muscular dystrophy (DMD) candidate domagrozumab on disappointing results in a mid-stage efficacy trial. ... Pfizer still has an iron in the DMD fire, in the form of its

  • Mallinckrodt doses first patient in muscular dystrophy trial Mallinckrodt doses first patient in muscular dystrophy trial

    DMD is caused by a lack of functional dystrophin protein, which assists in keeping muscles healthy. ... Mallinckrodt’s step forward comes shortly after another UK biotech, Summit Therapeutics, saw its shares go into freefall in June after its DMD

  • Summit plunges after Duchenne disappointment Summit plunges after Duchenne disappointment

    Shares in UK biotech Summit Therapeutics plunged 80% after its treatment for Duchenne muscular dystrophy (DMD) failed in phase II trials. ... Nevertheless Glyn Edwards warned that cutbacks at the company would now be inevitable after losing its DMD

  • Sarepta soars on positive Duchenne data Sarepta soars on positive Duchenne data

    Some studies have suggested that just 15% dystrophin expression is enough to prevent the contraction-induced muscle injury that characterises DMD. ... around 15% of DMD patients and has to be administered continually to exert its effects.

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Latest Intelligence

  • Pharma deals during November 2014 Pharma deals during November 2014

    additional $160m more in near-term milestones if drisapersen, the late-stage drug for Duchenne muscular dystrophy (DMD), secures “ early” approval. ... Prosensa has been busy since drisapersen failed a pivotal phase III for DMD (failure to beat a

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Latest appointments

  • Catabasis hires Rick Modi as its chief business officer Catabasis hires Rick Modi as its chief business officer

    We look forward to leveraging his capabilities as we advance our clinical development pipeline, particularly CAT-1004 for Duchenne muscular dystrophy (DMD), and our lipid programmes, CAT-2003 and CAT-2054.”. ... we seek to bring disease-modifying

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Latest from PMHub

  • The gene therapy revolution

    for instance to treat haemophilia, rare ophthalmic disorders and for Duchenne muscular dystrophy/DMD), genetic therapies are likely to represent a revolution in medicine over the coming years. ... However, in most areas where genetic treatments are being

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