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DPP-4 inhibitor

This page shows the latest DPP-4 inhibitor news and features for those working in and with pharma, biotech and healthcare.

FDA rejects AZ's diabetes combination

FDA rejects AZ's diabetes combination

The combination of DPP-4 inhibitor saxagliptin - sold by AZ as Onglyza - and SGLT2 inhibitor dapagliflozin (marketed as Farxiga/Forixiga) is considered to be a key component of the company's ... DPP-4 inhibitors are already widely used in diabetes and

Latest news

  • Merck gets first OK for once-weekly DPP-4 inhibitor Merck gets first OK for once-weekly DPP-4 inhibitor

    Merck gets first OK for once-weekly DPP-4 inhibitor. Marizev approved in Japan. ... That includes Merck's Januvia (sitagliptin), which is heading the DPP-4 inhibitor market with sales of almost $4bn last year.

  • Jardiance survival data wows diabetes conference Jardiance survival data wows diabetes conference

    Overall, the findings give Lilly and Boehringer a lift versus their rivals in oral type 2 diabetes therapy, as Merck &Co's DPP-4 inhibitor Januvia (sitagliptin) was shown in the

  • FDA clears Jardiance combo for type 2 diabetes FDA clears Jardiance combo for type 2 diabetes

    While their metformin combination lagged behind rivals, Boehringer and Lilly were the first to get approval in the US for a combination of an SGLT2 inhibitor with a DPP-4 inhibitor, ... Tanabe. A combination of Pfizer's developmental SGLT2 inhibitor

  • Boehringer returns to growth in first half Boehringer returns to growth in first half

    DPP-4 inhibitor Trajenta competes head-to-head with a number of other drugs in the class, including Novo Nordisk's which also grew 22% to reach 8.4bn Danish krone

  • AstraZeneca and its diabetes plans AstraZeneca and its diabetes plans

    Both AZ and BMS had been involved in a diabetes alliance since 2007 and have developed the DPP-4 inhibitor Onglyza (saxagliptin), the saxagliptin/metformin combination product Kombiglyze and the SGLT2 ... inhibitor Forxiga (dapagliflozin), all of which

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Latest Intelligence

  • Interview: Christopher Boulton, AstraZeneca Interview: Christopher Boulton, AstraZeneca

    Between them, the companies developed the DPP-4 inhibitor Onglyza (saxagliptin), the saxagliptin/metformin combination product Kombiglyze and the SGLT2 inhibitor Forxiga (dapagliflozin), all of which have received approvals in various ... The deal gives

  • Interview: Allan Hillgrove, Boehringer Interview: Allan Hillgrove, Boehringer

    Boehringer's interest in the area is a relatively recent one and is focused on its major partnership with Lilly, which so far has produced Trajenta – a DPP-4 inhibitor for

  • Pharma deals during April 2013 Pharma deals during April 2013

    The deal with AZ, in oncology, follows a preclinical feasibility study on an undisclosed AZ kinase inhibitor. ... standalone product and in combination with other drugs, including Januvia (Merck's blockbuster DPP-4 inhibitor) and metformin.

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