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Endocyte

This page shows the latest Endocyte news and features for those working in and with pharma, biotech and healthcare.

Merck's vintafolide fails ovarian cancer trial

Merck's vintafolide fails ovarian cancer trial. Major blow for drug’ s original developers Endocyte. ... Shares in Endocyte are currently hovering above $6.50, having traded as high as $33.70 in the last 12 months.

Latest news

EMA backs Janssen rare disease drug for approval

it. Staying in the orphan disease area the CHMP also gave the nod to Endocyte's Vynfinit (vintafolide), a treatment for platinum-resistant ovarian cancer, along with two companion diagnostic drugs
Boehringer/Lilly's empagliflozin among CHMP recommendations

There were also recommendations for four orphan drugs: Janssen-Cilag's Sylvant (situximab) and, along with the companion diagnostic drugs Folcepri (etarfolatide) and Neocepri (folic acid), Endocyte's Vynfinit (vintafolide).
Late-stage ovarian cancer

Endocyte's vintafolide is a folate-targeted conjugate composed of a folate molecule plus a vinca alkaloid, which acts as a microtubule destabilising agent. ... Phase III studies of vintafolide for the treatment of platinum-resistant ovarian cancer are
Merck's vintafolide shows its worth in ovarian cancer

unlikely to be superior to docetaxel alone, caused a massive reduction in the shares of Endocyte, the US firm which originally developed it. ... Along with Merck, Endocyte has been "building up our commercial capabilities to prepare for a potential
AZ licenses Merck ovarian cancer drug

vintafolide for ovarian cancer, which Merck licensed from Endocyte last year in a deal valued at up to $1bn.

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Latest Intelligence

Charting a course for expansion

and eastern Europe - and US biotech Endocyte.

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Latest appointments

Endocyte appoints Parexel's Scot Harper to oversee clinical trials

Endocyte appoints Parexel's Scot Harper to oversee clinical trials. He also previously served at Novartis and Lilly. ... In addition, Endocyte says it has three new drug candidates scheduled to enter the clinic before the end of 2014.
Endocyte brings in senior figures from BMS and Amgen

Endocyte brings in senior figures from BMS and Amgen. Appoints Torsten Hoof and Ulf Staginnus as company prepares to launch cancer drugs. ... The two additions follow the hire in July 2012 of Endocyte's first chief commercial officer, David Meek from

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