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Esbriet

This page shows the latest Esbriet news and features for those working in and with pharma, biotech and healthcare.

Biogen loses another pipeline drug to toxicity concerns

Biogen loses another pipeline drug to toxicity concerns

In the interim, two drug treatments – Boehringer Ingelheim’s  Ofev(nintedanib) and Roche/Genentech’s  Esbriet(pirfenidone) – have been approved by the FDA for the disease and grown into blockbuster products

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  • Pharma deals during August 2014 Pharma deals during August 2014

    The prize: the FDA designated “breakthrough therapy” pirfenidone (Esbriet), an orally active small molecule, anti-fibrotic agent that inhibits the synthesis of both TGF-beta and TNF-alpha. Pirfenidone is under

  • Orphan indication? No easy access Orphan indication? No easy access

    Only the case of Intermune's idiopathic pulmonary fibrosis drug Esbriet (perfenidone) was the balance of benefit and risk to patients considered and a finding of 'no proven added benefit' was

  • Country report: The healthcare market in Germany Country report: The healthcare market in Germany

    Out of the 10 products assessed last year, four have obtained poor innovation scores: Esbriet (pirfenidone), Livazo (pitavastatin), Yellox (bromfenac) and Trajenta (linagliptin) and a majority of manufacturers have struggled – sometimes

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