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gemcitabine

This page shows the latest gemcitabine news and features for those working in and with pharma, biotech and healthcare.

Merck chases Roche with triple-negative breast cancer data for Keytruda

The actual progression-free survival (PFS) numbers for KEYNOTE-355 – which compared Keytruda plus Bristol-Myers Squibb/Celgene’s Abraxane (nab-paclitaxel), paclitaxel or gemcitabine/carboplatin to the chemo drugs given

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Lilly’s pegilodecakin fails in long-shot pancreatic cancer trial

after first-line gemcitabine-based treatment.
Keytruda monotherapy fails in triple negative breast cancer

By contrast, Merck &Co’s phase 3 Keynote-119 trial evaluated Keytruda as a monotherapy for the second or third-line treatment compared to chemotherapy (capecitabine, eribulin, gemcitabine or vinorelbine). ... One such study is Keynote-355, which looks
Celgene’s Abraxane fails pancreatic cancer trial

Expectations for a positive outcome for the trial weren’t high, particularly as it used gemcitabine as a control. ... Since APACT was started, a new regimen called mFOLFIRINOX – based on oxaliplatin, leucovorin, irinotecan, and fluorouracil – has
CTI slumps as Servier-partnered lymphoma drug fails

gemcitabine in aggressive B-cell NHL, but found that CTI’s drug was unable to improve progression-free survival (PFS), its primary endpoint.
NICE knocks-back Shire's pancreatic cancer drug Onivyde

The watchdog was reviewing the treatment’s use in England and Wales for metastatic pancreatic cancer that has progressed after gemcitabine-based therapy.

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The rise of chronic disease in BRIC markets

For late-stage patients, Brazil physicians are more likely to use an anthracycline-based regimen without a taxane in the first line, gemcitabine, paclitaxel or a combination of both in the

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Battling breast cancer with precision medicine (Part 2)

I wanted her to access the best treatment possible. I also knew that carboplatin was especially effective when used with another chemotherapy called gemcitabine, as the two drugs are known to ... tested the PARP inhibitor with the gemcitabine-carboplatin
World Ovarian Cancer Day: Current treatments and future hopes for ovarian cancer

Unfortunately, recurrence rates in high-grade ovarian cancer mean that platinum resistance is a very real possibility, leaving second-line treatment such as gemcitabine, topotecan or liposomal doxorubicin less effective over
Marketing strategy in complex environments

cells. A good example of this is the combined use of Abraxane and gemcitabine in the treatment of metastatic adenocarcinoma of the pancreas – Abraxane helps to inhibit cancer cell growth, and ... gemcitabine encourages apoptosis of cell

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