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heart failure
This page shows the latest heart failure news and features for those working in and with pharma, biotech and healthcare.
Moderna CEO makes case for firm’s lofty valuation
Three additional candidates are due to reach the phase 2 testing stage this year, joining Moderna’s AstraZeneca-partnered VEGF-A candidate for heart failure which is its lead project.
Latest news
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Astellas makes another gene therapy play with Juventas deal
The choice of lead indication for JVS-100 is an interesting one, given that the therapy also has potential in other, more life-threatening indications such as chronic heart failure (CHF)
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Novartis’ heart failure drug Entresto proves superior to enalapril
Entresto is currently approved in Europe for the treatment of symptomatic chronic heart failure with reduced ejection fraction. ... In the US it is indicated for the treatment of heart failure in patients with systolic dysfunction.
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Moderna files record $500m IPO for RNA pipeline
AstraZeneca-partnered VEGF drug AZD8601 is currently heading the pipeline and is in phase 2 for heart failure, and following after are phase 1-stage vaccines for solid tumours and lymphoma,
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AZ says target of $45bn sales by 2023 still achievable
The study showed Farxiga cut hospitalisations for heart failure and cardiovascular death in a broad patient population, although it missed a secondary endpoint on major adverse cardiovascular events (MACE). ... It will be followed by additional studies
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Lilly trumpets Trulicity heart data in face-off with Novo Nordisk
cardiovascular disease, says Lilly, as less than a third (31%) of patients had established heart disease at enrolment. ... Meanwhile Boehringer and Lilly also have new real-world data for Jardiance from a patient registry, showing that the drug was able
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Latest Intelligence
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No incentive for a cure
The paradox of ‘cost-effective but unaffordable’ life-saving medicines. Type 1 diabetes, heart failure, HIV - all examples of diseases that have transitioned from fatal conditions to chronic diseases, thanks to
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Can value-based healthcare take off and reach for the skies?
costs. It was then backed with a ‘no response-no payment’ contract. It has also struck novel reimbursement packages with its heart failure therapy Entresto and its psoriasis treatment Cosentyx.
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Deal Watch February 2017
Sale of Priority Review Voucher (PRV). 125. Cytokinetics/ Royalty Pharma. 4.5% royalty on global sales of omecamtiv mecarbil for heart failure (phase III).
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Deal Watch January 2017
1, 700. Ionis | Akcea. Novartis. Exclusive option to licence. AKCEA-APOCIII-LRx for heart failure.
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A healthy challenge
All told, 50 million people in the EU are afflicted by conditions such as diabetes, congestive heart failure, chronic obstructive pulmonary disease and asthma, and in 2013 more than 1.2m
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Latest appointments
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uniQure appoints chief executive officer
for congestive heart failure and Huntington's disease into the clinic.”.
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Cardio3 BioSciences appoints Warren Sherman chief medical officer
Sherman has over 30 years' cardiology experience, with a focus on cell-based therapies for treating patients post-myocardial infarction and with heart failure.
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Acorda appoints new CFO
pain and heart failure. .
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Cardioxyl appoints Novartis scientist as chief medical officer
Dr Foo was responsible for the establishment and execution of multiple programmes in heart failure and the cardiorenal space at Novartis and will use her experience to lead research at ... Her unique combination of both early- and late-stage
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CytomX makes senior changes following Pfizer deal
Prior to this period at Affymax, Dr Polu was executive director, global development at Amgen, where he worked in the development of products in nephrology, diabetes and heart failure.
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Latest from PMHub
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ECHO Medical Communications
ECHO delivers dedicated medical communications specialising in the areas of endocrinology, cardiovascular disease, heart failure and obesity.
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ECHO Medical Communications
ECHO delivers dedicated medical communications specialising in the areas of endocrinology, cardiovascular disease, heart failure and obesity.
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90TEN shortlisted with six entries at the Communiqué Awards across PR and medical education
The campaigns span psoriasis, heart failure and HIV and cover medical education and PR, but they all have one thing in common: the power to change lives. ... Shining a light on heart failure management in the UK (90TEN and Novartis) – Excellence in
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Case Study: Qualitative research with payers in low and middle income countries
Our client wanted to understand in detail the usage decision drivers, triggers and processes for a high-cost innovative Acute Heart Failure (AHF) drug used in the acute emergency setting in
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Cogora
Excellence in Communications via Meetings - CORE: Hand-in-hand in heart failure – Shortlisted. ... Excellence in Collaboration and Partnerships’- CORE: Hand-in-hand in heart failure – Winner.
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Approximately 1 fully matching, plus 5 partially matching documents found.
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