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heart failure therapy

This page shows the latest heart failure therapy news and features for those working in and with pharma, biotech and healthcare.

Amgen, Servier start second phase 3 trial of heart failure hope

Amgen, Servier start second phase 3 trial of heart failure hope

Treatment is one of few in underserved area. Amgen and Servier have decided to run a second phase 3 trial of omecamtiv mecarbil in heart failure, as their first pivotal study ... One advance in drug treatment was the launch of Novartis’ Entresto

Latest news

  • Novartis’ heart failure drug Entresto proves superior to enalapril Novartis’ heart failure drug Entresto proves superior to enalapril

    In the US it is indicated for the treatment of heart failure in patients with systolic dysfunction. ... Though the results are hardly surprising considering Entresto was discovered as the first chronic heart failure therapy to show an improvement over

  • NICE says no to AZ and Vifor’s rival hyperkalaemia drugs NICE says no to AZ and Vifor’s rival hyperkalaemia drugs

    Most common in patients with poor kidney function, heart failure or liver disease, hyperkalemia can be fatal, and patients have had few options for treatment until now. ... Hyperkalaemia is also seen in patients taking common medications for heart failure

  • Novartis follows Pfizer and freezes US prices this year Novartis follows Pfizer and freezes US prices this year

    Novartis’ decision to keep pricing steady has been helped by a rosy set of second-quarter results, with recent launches Cosentyx (secukinumab) for psoriasis and heart failure therapy Entresto (sacubitril and ... for diffuse large B-cell lymphoma (DLBCL)

  • Novartis negotiates ex-US rights to Spark gene therapy Novartis negotiates ex-US rights to Spark gene therapy

    Gene therapy is a promising new avenue to potentially address this unmet need.”. ... The gains were driven by strong performances from new immunotherapy Cosentyx (secukinumab), which breached the $2bn sales threshold for the year, as well as heart

  • Celixir cleared to start trial of stem cell therapy for heart failure Celixir cleared to start trial of stem cell therapy for heart failure

    Heart failure is still a major cause of death affecting millions of patients worldwide [and] current therapies do not reduce chronic myocardial scarring, diminish disease progression or prolong life,” commented Prof ... We are assembling a world-class

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Latest Intelligence

  • Can value-based healthcare take off and reach for the skies? Can value-based healthcare take off and reach for the skies?

    CAR-T cell therapy for children with B-cell ALL. ... costs. It was then backed with a ‘no response-no payment’ contract. It has also struck novel reimbursement packages with its heart failure therapy Entresto and its psoriasis treatment Cosentyx.

  • Heart failure therapy embarks on a new era Heart failure therapy embarks on a new era

    the heart, and its proposed benefits have been backed up in clinical trials. ... failure by 18%  compared to placebo when given on top of standard HF therapy.

  • Pharma deals in April 2015 Pharma deals in April 2015

    uniQure has licensed its proprietary gene therapy programme for congestive heart failure, that is hoped will restore the heart's ability to synthesise S100A1, a calcium sensor and master regulator of ... to become available for common diseases such as

  • Pharma deals during October 2013 Pharma deals during October 2013

    heart failure (phase IIb). 75. ... 75. Trevena. TRV027, GPCR biased ligand for acute heart failure (phase II).

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Latest appointments

  • uniQure appoints chief executive officer uniQure appoints chief executive officer

    Kapusta had previously served as the gene therapy specialist's interim chief executive since September last year, as well as chief financial officer since January 2015. ... for congestive heart failure and Huntington's disease into the clinic.”.

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