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kinase inhibitor

This page shows the latest kinase inhibitor news and features for those working in and with pharma, biotech and healthcare.

Roche’s rival to Bayer’s Vitrakvi gets speedy FDA review

Roche’s rival to Bayer’s Vitrakvi gets speedy FDA review

Entrectinib is a tropomyosin receptor kinase (TRK) inhibitor that shuts down a range of tumour-associated pathways, including ROS1, NTRK and ALK, and has been tipped by analysts as a potential

Latest news

  • Biogen picks up another drug from wide-ranging Ionis alliance Biogen picks up another drug from wide-ranging Ionis alliance

    Among others in late-stage development are AB Sciences’ tyrosine kinase inhibitor masitinib, which was turned down by the CHMP in April at its first attempt for EU approval, and Orion

  • BMS CEO tackles investor ‘frustrations’ on immuno-oncology BMS CEO tackles investor ‘frustrations’ on immuno-oncology

    BMS was the pathfinder for the checkpoint inhibitor market with its CTLA4 inhibitor Yervoy (ipilimumab) and PD-1 blocker Opdivo (nivolumab), However, it has since lost ground to rival Merck ... inhibitor Bavencio (avelumab) – both given in tandem with

  • Merck’s Bavencio joins first-line kidney cancer face-off Merck’s Bavencio joins first-line kidney cancer face-off

    The JAVELIN Renal 101 study reported at this week’s ESMO conference paired Merck’s immuno-oncology drug Bavencio (avelumab) with Pfizer’s tyrosine kinase inhibitor Inlyta (axitinib), and revealed a ... inhibitor and TKI has emerged as an “early

  • A look ahead to key trial readouts at ESMO A look ahead to key trial readouts at ESMO

    101 study, the first time that a checkpoint inhibitor has shown an increase in progression-free survival (PFS) when combined with a tyrosine kinase inhibitor – in this case Pfizer’s Inlyta ... for its MAGE-A10-targeting cell therapy in non-small cell

  • FDA approval gained, Pfizer sets sights on first-line NSCLC market FDA approval gained, Pfizer sets sights on first-line NSCLC market

    Vizimpro could challenge Tagrisso, survival data will be key. Pfizer’s gruelling trek to bring EGFR inhibitor dacomitinib to market has finally paid off, with the FDA approving it as a ... The second-generation EGFR tyrosine kinase inhibitor has been

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Latest Intelligence

  • Deal Watch January 2018

    The headline value contains significant sales milestones linked to performance of Impact's lead phase III stage asset fedratinib, an oral JAK2 kinase inhibitor in development for the treatment of myelofibrosis ... Acquisition company -  remaining 90%. 9

  • Deal Watch September 2016 Deal Watch September 2016

    No financial terms were disclosed. Genentech signed an exclusive licence [global excluding South Korea] with Hanmi Pharmaceutical to develop and market HM95573, a pan-RAF inhibitor. ... 1, 000+. Hanmi / Genentech. Licence. HM95573, a selective

  • Deal Watch June 2016 Deal Watch June 2016

    acquisition assets. 350. CrystalGenomics/ Aptose Biosciences. CG026806 inhibitor of Bruton's tyrosine kinase, FMS-like tyrosine kinase 3 and Aurora kinases (preclinical). † ... acquisition company. 105. Nektar Therapeutics/ Daiichi Sankyo Europe.

  • Deal Watch May 2016 Deal Watch May 2016

    Paying a 55% premium at $99.25 per share, the acquisition brings crisaborole, a topical PDE4 inhibitor for mild to moderate atopic dermatitis (eczema) with estimated peak sales of $2bn. ... 282. Carna Biosciences/ ProNAi Therapeutics. Licence. $0.9m

  • Pharma deals in September 2015 Pharma deals in September 2015

    Purdue licensed VM Pharma's allosteric selective tropomyosin receptor kinase A (TrkA) inhibitor programme for chronic pain. ... Collaboration - public private partnership. 220. VM Pharma. Purdue Pharma. VM902A a signalling protein tropomyosin receptor

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