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KRAS

This page shows the latest KRAS news and features for those working in and with pharma, biotech and healthcare.

Amgen aims for first KRAS inhibitor approval in the US

Amgen aims for first KRAS inhibitor approval in the US

If approved, it would become the first therapy designed to target the KRAS pathway, an oncogene that is implicated in around a third of all human cancers. ... In NSCLC, KRAS G12C is the most common KRAS mutation, with around 13% of patients with NSCLC in

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  • Encouraging signs in biomarker R&D Encouraging signs in biomarker R&D

    The questions being asked are, what does an individual’s mutational profile look like, and do we have a drug to treat it; ie, do they have EGFR mutations, KRAS or

  • Interview: AstraZeneca's Susan Galbraith Interview: AstraZeneca's Susan Galbraith

    This includes people with NSCLC who have a mutated KRAS gene - an area where no specific treatment option exists. ... With selumetinib you've now got that plus another 20-25 per cent of NSCLC cases - people with the KRAS mutation.”.

  • Pharma deals during September 2012 Pharma deals during September 2012

    advanced KRAS; a wild-type metastatic colorectal cancer (mCRC). ... 665. Symphogen / Merck KGaA. Product licence. Sym004 for advanced KRAS; a wild-type metastatic colorectal cancer (mCRC) (phase I /II).

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