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Mediator

This page shows the latest Mediator news and features for those working in and with pharma, biotech and healthcare.

FDA finally approves Shire’s potential blockbuster Xiidra

FDA finally approves Shire’s potential blockbuster Xiidra

In vitro studies suggested that lifitegrast may inhibit T cell adhesion to ICAM 1 in a human T-cell line and secretion of inflammatory mediators (cytokines) in human peripheral blood mononuclear

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  • Searching for health Searching for health

    The task of conducting the diverse themes needed for innovation is never easy and, in France, it is made even harder by the lingering echoes from the Mediator scandal.

  • Compulsory evaluation in France Compulsory evaluation in France

    The direction of travel shouldn't come as too much of a surprise, following the PIP breast implant health scare and the subsequent scandal around diabetes drug Mediator (benfluorex).

  • The impact of Hollande's healthcare reforms in France The impact of Hollande's healthcare reforms in France

    Servier's diabetes drug, Mediator was being prescribed as an appetite suppressant for decades, when it was pulled from the market, over safety concerns in 2009. ... An estimated 5 million people took Mediator in France and it was reimbursed at 65 per cent

  • Interview: Trevor Smith, Takeda Interview: Trevor Smith, Takeda

    France's AFSSAPS, which has since been dissolved, acted quickly – some might say hastily – having been criticised heavily for its role in the 2011 Mediator scandal, which saw Servier's diabetes

  • Revolution or evolution: is it the end of SMR and ASMR in France? Revolution or evolution: is it the end of SMR and ASMR in France?

    The 2011 HAS annual report mentions the imminent end of the SMR and ASMR, arguing that the Mediator affair challenged the relevance of these two criteria.

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