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NASH

This page shows the latest NASH news and features for those working in and with pharma, biotech and healthcare.

Merck enters agreement with Hanmi for investigational NASH drug

Merck enters agreement with Hanmi for investigational NASH drug

The deal with Hanmi builds on Merck’s existing NASH pipeline, which includes a mid-stage candidate, NGM313, licensed from NGM Biopharmaceuticals last year. ... NGM313 is an antibody targeting the beta-Klotho/FGFR1c receptor complex that could represent

Latest news

  • Genfit scraps phase 3 trial of experimental NASH drug Genfit scraps phase 3 trial of experimental NASH drug

    Drug failed to meet primary endpoint in interim analysis. Genfit has put the brakes on a late-stage trial of its experimental nonalcoholic steatohepatitis (NASH) drug elafibranor after reporting disappointing results ... The phase 3 RESOLVE-IT trial was

  • Bayer signs €250m pact with India’s Curadev for STING drugs Bayer signs €250m pact with India’s Curadev for STING drugs

    Excessive signalling through cGAS–STING has been linked to a range of chronic and rare diseases, including neurodegenerative conditions like Parkinson’s, pulmonary fibrosis and non-alcoholic steatohepatitis (NASH).

  • Zydus Cadila scores first ever NASH approval, in India Zydus Cadila scores first ever NASH approval, in India

    Saroglitazar will provide hope and new lease of life for millions of patients in India suffering from NASH,” he added. ... Another potential treatment for NASH – from Intercept – is currently under review with the US Food and Drug Administration

  • FDA delays decision on Intercept's NASH drug by three months FDA delays decision on Intercept's NASH drug by three months

    As it stands, Intercept is poised to access the NASH market before its larger rivals but it is unclear if that first-mover advantage will translate into commercial success. ... Diagnosis is another potential barrier to sales growth. NASH is definitively

  • Boehringer bolsters NASH pipeline with Enleofen link-up Boehringer bolsters NASH pipeline with Enleofen link-up

    Boehringer Ingelheim has added another platform in its fibrotic disease R&D, partnering with Enleofen on preclinical-stage interleukin-11 inhibitors with potential in non-alcoholic steatohepatitis (NASH). ... Despite many attempts there is still no

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Latest Intelligence

  • Keeping up the fight against HIV and using the lessons to tackle other threats Keeping up the fight against HIV and using the lessons to tackle other threats

    Gilead, which has suffered two recent NASH therapy trial knock-backs, believes medical and scientific advances need to be welded to comprehensive patient engagement to engineer effective responses to what is ... being labelled as the next public health

  • Deal Watch October 2018

    treatments for NASH with Pfizer products. Not. disclosed. One of the big deals for Novartis these last two months was the long‐rumoured sale of it’s Sandoz division’s US ... The agreement is driven by the belief that liver diseases will respond

  • Taking a lean and careful approach Taking a lean and careful approach

    A lot of NASH patients also have these conditions so we want to look at and understand the underlying causes to see what else we can come up with there.”. ... The NASH market is expected to be worth $20bm by 2025 and financial brokers recently valued

  • 2016: The year when deal-makers took stock? 2016: The year when deal-makers took stock?

    Oncology, immuno-oncology and central nervous system therapies once again topped the charts, but 2016 also saw the emergence of new areas, notably non-alcoholic steatohepatitis or NASH. ... With NASH appearing to be a long-term consequence of obesity it

  • Deal Watch December 2016 Deal Watch December 2016

    The Scandinavian company, Nuevolution, uses its drug discovery platform Chemetics to discover novel small molecules in the field of chronic inflammatory diseases, including psoriasis, rheumatoid arthritis, non-alcoholic steato-hepatitis (NASH),

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