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neurodegeneration

This page shows the latest neurodegeneration news and features for those working in and with pharma, biotech and healthcare.

Mintun, vice president of pain and neurodegeneration at Lilly.

Muna raises $73m to advance neurodegenerative disease-focused small molecule pipeline

The platform, based on work from the De Strooper and Glerup labs, considers the disease pathology of and resilience to neurodegeneration.
Annovis Bio’s lead therapeutic shows ‘significant improvements’ in Alzheimer’s, Parkinson’s

The toxic cascade in neurodegeneration begins with high levels of neurotoxic proteins, which impair axonal transport, increase inflammation and eventually lead to nerve cell death and permanent loss of cognition and
Merck & Co signs deal with Amathus for neurodegenerative diseases

Collaboration will focus on developing small molecules for undisclosed disease targets
Roche, Genentech partner with The Weill Neurohub on ten-year neuroscience collaboration

The initial areas of focus for the ATN are neurodegeneration, CRISPR-based therapeutics, protein degradation, functional genomics in human brain cells and sleep mechanisms and circuits.
Lilly picks up gene therapy programme in $1bn Prevail Therapeutics acquisition deal

assets,” said Mark Mintun, vice president of pain and neurodegeneration research at Lilly.

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A roadmap to the successful treatment of Alzheimer’s disease

Two proteins – Tau and beta-amyloid – are recognised as major hallmarks of neurodegeneration: tangles and other abnormal forms of Tau protein accumulate inside the brain cells and spread between cells, while ... Secondly, it is well understood that
Brain power: fresh approaches to Alzheimer’s drug discovery

US biotech company Alector, which is pioneering work in immuno-neurology and novel therapeutic approaches to treating neurodegeneration, raised $176m in an initial public offering in early February. ... Alector has devoted the last five years to the
Deal Watch October 2018

Dicerna/. Lilly. GalXC RNAi technology platform for targets in Cardiometabolic disease, neurodegeneration and pain.
Key considerations for disease- modifying Parkinson’s disease trials

dopamine due to neurodegeneration.
Holding on to hope for Alzheimer’s advances

abnormalities including seizures, neurodegeneration, cognitive deficits and hypomyelination…it is completely unclear whether BACE could be targeted in a manner to affect amyloid processing in a therapeutic manner, without serious

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Lilly strengthens team with in-house promotions

Importantly, this team will help us maintain focus as we work to bring forward new medicines in diabetes, cancer, immunology, neurodegeneration and pain.”.
Asceneuron appoints chief medical officer

He joins the neurodegenerative diseases specialist from Novartis, where he had served a s vice president of its neuroscience development franchise and therapeutic head for neurodegeneration since 2011.
Nouscom appoints COO and board members

Prior to this, she was the global head of neurodegeneration at Novartis, and worked in the healthcare sector of McKinsey &Company in Chicago.
Polleo Pharma co-founders join Chronos Therapeutics

Dr Murray (pictured above) brings over 20 years of drug discovery and early development experience to the role, spread across a range of therapeutic areas including dermatology, inflammation, neurodegeneration, psychiatry.
Sanofi appoints Pfizer's Rita Balice-Gordon to lead neurobiology research

including neurodegeneration, neuroinflammation and central nervous system inherited diseases.

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What do NHS changes and the Life Sciences Vision mean for medicines?

These seven challenges (or ‘’silent pandemics’ as the LSV calls them) are neurodegeneration; early diagnosis and treatment in cancer, including immune therapies; vaccine development and manufacturing; cardiovascular disease and obesity;
Are we ready for an Alzheimer's disease modifying treatment

As it is easier to prevent neurodegeneration (neuron death) than to reverse it, neuroscientists are starting to look for early markers, through genetic tests or blood tests, in order to diagnose
Innovative approaches in the treatment of multiple sclerosis

The pathogenesis of MS consists of two key components: focal inflammatory demyelination, and neurodegeneration.
Innovative approaches in the treatment of multiple sclerosis

The pathogenesis of MS consists of two key components: focal inflammatory demyelination, and neurodegeneration.

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