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PD-L1 inhibitors
This page shows the latest PD-L1 inhibitors news and features for those working in and with pharma, biotech and healthcare.
Gilead makes a play for novel cancer drug with Tizona deal
anti-PD-1/L1 therapies and deepen responses in tumours that are sensitive to these treatments. ... Gilead, however, is looking past PD-1/L1 inhibitors to the next class of transformative treatments, with its play for Tizona just the latest in a string of
Latest news
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Tecentriq misses the mark in advanced ovarian cancer
Tecentriq is part of a new class of immunotherapy treatments, also known as PD-1/L1 inhibitors, that have transformed the market over the last few years. ... The FDA approval for Imfinzi makes AZ’s drug the first PD-1/PD-L1 inhibitor to challenge
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Merck KGaA, Pfizer’s Bavencio stumbles in head and neck cancer
PD-L1 inhibitor – this time stumbling in head and neck cancer. ... 1/PD-L1 inhibitors spilling across a number of cancer types and ramping up the competition.
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AstraZeneca’s Imfinzi fails first-line bladder cancer test
PD-L1 inhibitor Imfinzi (durvalumab) – given on its own and in combination with experimental CTLA4 inhibitor tremelimumab – wasn’t able to improve overall survival in patients with advanced (stage IV) bladder ... In the trial, Imfinzi monotherapy
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Immutep spikes on trial of its LAG-3 drug with Keytruda
The PD-1/PD-L1 checkpoint inhibitors that hit the market in 2015 have already transformed the standard of care for some cancers, but there is still a sizeable patient population ... so “the results showing an almost 50% [response] across all patients
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Innate Pharma and AstraZeneca take monalizumab into phase 3
AZ has vested interested in Innate’s candidate because of data which shows that it can improve the effectiveness of PD-1/PD-L1 inhibitors like AZ’s own Imfinzi (durvalumab).
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Latest Intelligence
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Immuno-oncology in 2019: the rapid evolution continues
In addition to the PD-1 inhibitors Keytruda and Opdivo, there are four PD-L1 inhibitors: Roche’s Tecentriq, AstraZeneca’s Imfinzi, Pfizer and Merck’s Bavencio and Sanofi and ... PD-1/PD-L1 inhibitors: Keytruda is King, but the market is developing
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The good, the bad and the ugly
Companies are looking to pair their PD-1/PD-L1 checkpoint inhibitors with a variety of other agents to stimulate a more robust anticancer immune response,” says Xuan.
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European venture funding for the life science sector
is likely to accelerate interest - the sheer number of combination therapies and PD-1/PD-L1 inhibitors could result in a commoditisation of this area that could threaten returns for venture
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Medius Deal Watch table for March 2015
170. Checkpoint Therapeutics / TG. Licence and collaboration. Human anti-PD-L1 and anti-GITR antibody preclinical programmes for haematological cancers. ... CAR-T and checkpoint inhibitors PD-1 and PD-L1. 110. Transtech / Calithera.
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Deal Watch table for November 2014
PD-L1 and PD-1 CP inhibitors. Co-development and co-marketing alliance. 2, 850. ... FPA008 mAb inhibits (CSF1R) to be combined with nivolumab (PD-1 check-point inhibitor).
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