RNA interference

This page shows the latest RNA interference news and features for those working in and with pharma, biotech and healthcare.

FDA clears Alnylam’s second RNAi drug for rare disease

Alnylam has claimed a second US approval for one of its RNA interference (RNAi) drugs, getting an FDA nod for acute hepatic porphyria drug Givlaari.

Eli Lilly shutters UK neuroscience unit, with 80 job losses expected

It also said shifting the neuroscience projects to the US will make it easier for Lilly apply new technologies like RNA interference and gene therapy to the neuroscience projects.
Arbutus hit hard as new hep B drug fails on safety

Last December, the company reported disappointing results in a phase 2 trial of a RNA interference candidate called ARB-1467, handing a competitive advantage to Arrowhead Pharmaceuticals whose rival drug ... It has since abandoned the programme in favour
ACPs to lead gene therapies in haemophilia market growth

The two drugs have distinct mechanisms – Hemlibra is a bispecific factor IXa- and factor X-directed antibody, while fitusiran is an RNA interference (RNAi) therapeutic targeting the endogenous anticoagulant antithrombin (AT) –
Twentyeight-Seven raises another $15m for non-coding RNA drugs

This is a different approach to the emerging class of RNA therapeutics that target RNA that is directly involved in protein expression, such as antisense and RNA interference (RNAi) drugs from ... leader in capitalising on the emerging science around RNA
Biotech now vital to pipelines – but success rates falling

first RNA interference (RNAi) therapy and Lox/Bayer’s NTRK gene fusion – targetting Vitrakvi (larotrectinib).

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Silence appoints chief medical officer

These studies involve Silence's investigational portfolio of RNA interference (RNAi) therapeutics, which aim to treat conditions by selectively turning off genes expressed in an individual with a certain disease.

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