tenofovir alafenamide

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ViiV’s two-drug HIV combo backed by CHMP

Its main rival is expected to be Gilead’s new fixed-dose regimen Biktarvy, which combines integrase inhibitor bictegravir with the two ingredients in its fast-growing Descovy (emtricitabine/tenofovir alafenamide)

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Gilead says switching studies back new HIV therapy Biktarvy

The results of Study 1844 showed that patients who transferred to treatment with Biktarvy (bictegravir/emtricitabine/tenofovir alafenamide) from Triumeq (abacavir/dolutegravir/lamivudine) were able to maintain their viral suppression over
Gilead’s triple HIV drug approval prompts GSK lawsuit

GSK’s ViiV Healthcare unit has filed a lawsuit against Gilead claiming that its integrase inhibitor bictegravir - which is one of the active ingredients of Biktarvy along with emtricitabine and tenofovir ... alafenamide (TAF) - infringes its patent
GSK’s ViiV gets US okay for two-drug HIV regimen

that adds integrase inhibitor bictegravir to the two ingredients in its fast-growing Descovy (emtricitabine/tenofovir alafenamide) product.
Positive trial results for Janssen’s Symtuza boosts its HIV credentials

The STR provided ‘effective’and ‘durable’viral suppression. Janssen’s darunavir-based single tablet regimen (STR) Symtuza (darunavir/cobicistat/emtricitabine/tenofovir alafenamide) showed a positive outcome in the treatment of HIV
Janssen wins European approval for Symtuza

It’s the first complete, single-tablet regimen (STR) based on its big-selling protease inhibitor Prezista (darunavir), which it combines with cobicistat, emtricitabine and tenofovir alafenamide (TAF). ... Results from a bioequivalence study that

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Choices, choices: the rapidly evolving HIV treatment landscape

With Triumeq signalling the approval of the first STR without tenofovir disoproxil fumarate (TDF) it can, uniquely, be used in those patients with impaired kidney function. ... Gilead, in hot pursuit, is in phase III of development of a new regimen where

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