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tramiprosate

This page shows the latest tramiprosate news and features for those working in and with pharma, biotech and healthcare.

Alzheon says data backs potential of Alzheimer's candidate

Alzheon says data backs potential of Alzheimer's candidate

The cognitive effect increased significantly with time, suggesting a potential disease-modifying effect of tramiprosate," they conclude. ... Tramiprosate is thought to work by inhibiting the aggregation of beta amyloid monomers into toxic oligomers.

Latest news

  • Amyloid-targeting Alzheimer's drug bapineuzumab in phase III failure Amyloid-targeting Alzheimer's drug bapineuzumab in phase III failure

    The results have not come as a surprise, however, as several other drugs designed to target amyloid have already failed in trials - including Neurochem's Alzhemed (tramiprosate), Lundbeck/Myriad Genetics' Flurizan

  • 2012: amyloid as Alzheimer’s target?

    The number of disappointments for amyloid-targeting drugs is fairly substantial. Two small-molecule candidates, Neurochem's Alzhemed (tramiprosate) and Lundbeck/Myriad Genetics' Flurizan (r-flurbiprofen), failed a few years ago,

  • Signalling change

    Another once-promising anti-amyloid drug, tramiprosate, was also abandoned by Bellus Health due to inconclusive phase III study findings.

  • Halted in its tracks

    Tramiprosate is a B-amyloid inhibitor that is currently in phase III development with Neurochem. ... Data presented at ICAD 2006 showed tramiprosate halts B-amyloid-induced neuronal cell death in rats.

  • Dealing with dementia

    A promising late-stage candidate is Neurochem's Alzhemed (tramiprosate). This drug works by mimicking and binding to glycosaminoglycan (GAG), which promotes the formation of the amyloid-beta plaques.

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