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trial failures

This page shows the latest trial failures news and features for those working in and with pharma, biotech and healthcare.

Realm toppled by second mid-stage trial flop

Realm toppled by second mid-stage trial flop

PR022 did not show the desired effect in this trial, ”said Alex Martin, the biotech’s CEO. ... considerably after the twin trial failures.

Latest news

  • Reviews start for Pfizer’s wildcard lung cancer drug dacomitinib Reviews start for Pfizer’s wildcard lung cancer drug dacomitinib

    Regulatory reviews have started for Pfizer’s non-small cell lung cancer drug dacomitinib on both sides of the Atlantic, four years after a pair of trial failures left its future ... Dacomitinib missed its objectives in two phase III trials reported in

  • Pharma sales help Bayer escape the worst from a bumpy 2017 Pharma sales help Bayer escape the worst from a bumpy 2017

    easy”. For its pharmaceuticals business the ‘downs’included several late-stage trial failures towards the end of the year. ... Among them were a 7, 000 patient study of Xarelto in secondary stroke, a combination trial of Eylea and a drug-device

  • Merck BACE inhibitor adds to litany of Alzheimer's trial failures Merck BACE inhibitor adds to litany of Alzheimer's trial failures

    Merck BACE inhibitor adds to litany of Alzheimer's trial failures. Interim data shows “ virtually no chance” of clinical success for verubecestat. ... The EPOCH trial enrolled patients with established mild-to-moderate Alzheimer symptoms and was due

  • Choose or lose Choose or lose

    In essence, it involves sifting through thousands of 'industry episodes' such as launches, trial results, acquisitions and failures. ... The latest trial results from Amgen point out how its model is trying to create clear space from statins.

  • Tau protein drug fails late-stage trial Tau protein drug fails late-stage trial

    Tau protein drug fails late-stage trial. Alzheimer’ s disease therapy only showed benefit in patients with no existing treatments. ... Much of the pharma industry's efforts in Alzheimer's have been directed at the amyloid plaques seen in the brains of

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Latest Intelligence

  • Interview: AstraZeneca's Susan Galbraith Interview: AstraZeneca's Susan Galbraith

    major trial failures meaning the company was looking unlikely to fill the void created by patent expiries of key drugs.

  • An eye towards the biobetter in South Korea An eye towards the biobetter in South Korea

    Smaller entities such as Isu Abxis are listed companies whose stock prices and financial stability are especially vulnerable to trial failures. “ ... Some companies already have their biobetter pipelines in clinical trial stage.

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