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Xtandi

This page shows the latest Xtandi news and features for those working in and with pharma, biotech and healthcare.

Trial backs role for Lynparza in second-line prostate cancer

Trial backs role for Lynparza in second-line prostate cancer

In the 340-patient trial,   Lynparza was compared to hormonal treatment with Pfizer’s Xtandi (enzalutamide) or Johnson &Johnson’s Zytiga (abiraterone acetate) in this second-line setting, focusing on patients ... previously treated with Zytiga,

Latest news

  • Bayer bags FDA nod for early prostate cancer drug darolutamide Bayer bags FDA nod for early prostate cancer drug darolutamide

    now subject to generic competition – as well as Pfizer/Astellas’ Xtandi (enzalutamide). ... Zytiga is only approved for metastatic CRPC and, as Xtandi and Erleada were only approved for non-metastatic CRPC in the last few months, Nubeqa has an

  • Pfizer adds Array to cancer arsenal with $11bn acquisition Pfizer adds Array to cancer arsenal with $11bn acquisition

    cancers, where it has the blockbusters Ibrance and the Astellas co-marketed prostate cancer treatment Xtandi. ... The 2016 Medivation buyout saw its value drop when Xtandi failed to live up to expectations, and a late stage PARP inhibitor failed in phase

  • Bayer gains FDA priority review for prostate cancer drug Bayer gains FDA priority review for prostate cancer drug

    Once approved, the drug will go up against Johnson &Johnson’s Zytiga (with the first generics now reaching the market), its follow-up Erleada, and Pfizer/Astellas' Xtandi. ... Darolutamide won’t have an easy time competing in against these products,

  • Bayer, Orion prep challenge in prostate cancer market Bayer, Orion prep challenge in prostate cancer market

    Astellas said in its latest results statement that Xtandi made around $2.2bn in the first nine months of fiscal 2018/19, while J&J banked around $3.5bn from Zytiga ... Pfizer and Astellas have just reported positive results from the ARCHES trial of

  • Merck puts prostate cancer firmly in Keytruda’s sights Merck puts prostate cancer firmly in Keytruda’s sights

    not yet approved for prostate cancer but making its way through late-stage testing – as well as chemotherapy with docetaxel and prednisone, and hormone therapy with Astellas/Pfizer’s Xtandi (enzalutamide) ... Meanwhile, the chemotherapy combination

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Latest Intelligence

  • Drug launches to watch in 2019 Drug launches to watch in 2019

    Analysts believe the drug could achieve peak sales of around $1.7bn, but will face fierce competition from the likes of Pfizer and Astellas’ established Xtandi. ... It also gives J&J a leg-up in what looks set to be a big market tussle with Pfizer and

  • Deal Watch August 2016 Deal Watch August 2016

    35! Although Pfizer pointed to the $2.2bn of Xtandi sales for advanced metastatic prostate cancer, this product has been under licence to Astellas since 2009, including a US profit share ... Headline £m. Medivation (US). Pfizer (US). Company acquisition.

  • Deal Watch May 2016 Deal Watch May 2016

    The prize of course is the one marketed product in Medivation's portfolio, Xtandi [enzalutamide for the treatment of advanced prostate cancer] with sales estimated to reach $1.5bn and already

  • Deal Watch March 2016 Deal Watch March 2016

    Only one other deal had an upfront value of more than $1bn: the sale by UCLA to Royalty Pharma of its royalty rights to Xtandi with a cash payment of ... Research collaboration. $2, 258. UCLA/ Royalty Pharma. Xtandi – androgen receptor inhibitor.

  • Astellas: Ten years young Astellas: Ten years young

    Its efforts to date in oncology have seen it form a prostate cancer franchise on the back of Eligard (leuprolide acetate) and more recently Xtandi (enzalutamide). ... There it is currently conducting a series of investigations in breast cancer to assess

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Latest appointments

  • Dendreon appoints new R&D lead Dendreon appoints new R&D lead

    Joining from Astellas Pharma, Dr Brown most recently served as senior medical director of oncology, where he led US medical strategy for the prostate cancer drug Xtandi (enzalutamide).

  • Astellas promotes John Demaree Astellas promotes John Demaree

    Demaree was promoted from his position as executive director of oncology marketing, where he oversaw the launch of prostate cancer drug Xtandi (enzalutamide) and promotion of lung cancer therapy Tarceva (erlotinib).

  • Astellas makes senior EMEA appointments Astellas makes senior EMEA appointments

    Both men are veterans of Astellas. Dew joined the company in 2006 as senior manager business development and has worked on major products such as Xtandi.

  • Astellas poaches new oncology head from Takeda Astellas poaches new oncology head from Takeda

    She will now lead Astellas' efforts in cancer, which include prostate cancer drug Xtandi (enzalutamide) and Tarveca (erlotinib) – a lung cancer drug co-marketed by Roche.

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