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PMLiVE Top Pharma List

18

Revenue 2017

Epclusa

The Top Pharma List's top 50 pharmaceutical products by global sales ranking is compiled from GlobalData's pharmaceutical revenue figures. Epclusa was produced by Gilead Sciences.

Gilead gets OK for three-in-one hep C therapy in US

Gilead gets OK for three-in-one hep C therapy in US The single-tablet triple therapy contains NS5B polymerase inhibitor sofosbuvir and NS5A inhibitor velpatasvir - the two active ingredients in Gilead's recently-approved two-drug HCV combination Epclusa - as well as ... Sovaldi and follow-ups Harvoni and

Two new hepatitis C therapies fast-tracked in Europe

Two new hepatitis C therapies fast-tracked in Europe It is dosed once daily as three oral tablets and is being billed as a rival to Epclusa, which is dosed over 12 weeks in all patients. ... Analysts at Leerink have previously predicted that combined sales of Harvoni, Sovaldi and Epclusa will be $2.5bn a

Gilead files hepatitis C salvage regimen in US

Gilead files hepatitis C salvage regimen in US The two other studies - POLARIS-2 and 3 - compared the triple combination regimen in treatment-naïve patients given for eight weeks to Epclusa given for 12 weeks. ... The SVR rates were comparable between the new regimen and Epclusa in both trials.

SMC approves Opdivo combo as first-line skin cancer treatment

SMC approves Opdivo combo as first-line skin cancer treatment Also backs Gilead’s Epclusa, Baxalta’s Oncaspar, AZ’s Lynparza and Amicus’ Galafold. ... Meanwhile, Gilead Sciences' chronic hepatitis C virus infection therapy Epclusa (sofosbuvir/velpatasvir) received SMC backing for the treatment of patients

Torrid times at Gilead lead to calls for a major M&A deal

Torrid times at Gilead lead to calls for a major M&A deal HIV portfolio sales down almost 10% to $7.5bn despite strong $533m start for Epclusa. ... start for latest entrant Epclusa (sofosbuvir and velpatasvir), which contributed $533m in the quarter.

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