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PMLiVE Top Pharma List

4

Revenue 2017

Herceptin

The Top Pharma List's top 50 pharmaceutical products by global sales ranking is compiled from GlobalData's pharmaceutical revenue figures. Herceptin was produced by Roche.

Double trial disappointment for Roche

Double trial disappointment for Roche Discontinues Alzheimer’s programme and finds Kadcyla no better than Herceptin in certain breast cancer. ... Herceptin (trastuzumab) in improving progression free survival in patients with a certain type of breast cancer.

Novartis' Afinitor fails frontline breast cancer trial

Novartis' Afinitor fails frontline breast cancer trial The BOLERO-1 trial looked at the benefits of adding Afinitor to standard treatment with anti-HER2 antibody Roche's Herceptin (trastuzumab) and paclitaxel as a first-line treatment, but Novartis' ... Afinitor conferred a seven-month improvement in PFS,

Merck to start major trial of Keytruda in breast cancer

Merck to start major trial of Keytruda in breast cancer The company (known as MSD outside the US) will test whether PD-1 inhibitor Keytruda (pembrolizumab) can reverse resistance to Roche's Herceptin (trastuzumab) in patients with HER2-positive breast cancer. ... The phase Ib/II trial - called PANACEA - will

BMS taps F-star Alpha for immuno-oncology drug

BMS taps F-star Alpha for immuno-oncology drug FS102 works differently to current HER2-targeted therapies such as Roche's Herceptin (trastuzumab) and Perjeta (pertuzumab), and is being developed specifically to meet the problem of resistance to those drugs.

Pressure put on Roche to cut Kadcyla's UK price

Pressure put on Roche to cut Kadcyla's UK price threshold. Kadcyla is an antibody-drug conjugate (ADC) that combines the monoclonal antibody in Herceptin (trastuzumab) with ImmunoGen's DM1, a cytotoxic payload designed to boost its ability to kill tumour

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