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PMLiVE Top Pharma List

16

Revenue 2017

Tecfidera

The Top Pharma List's top 50 pharmaceutical products by global sales ranking is compiled from GlobalData's pharmaceutical revenue figures. Tecfidera was produced by Biogen Idec.

Biogen’s R&D chief Ehlers heads for the exit

Biogen’s R&D chief Ehlers heads for the exit

There are more immediate problems at Biogen however. Multiple sclerosis blockbuster Tecfidera (dimethyl glutamate) is coming under increasing competitive pressure, and analysts aren’t confident that a follow-up with an ... improved tolerability profile

J&J’s ponesimiod tops Aubagio in head-to-head MS trial

J&J’s ponesimiod tops Aubagio in head-to-head MS trial market-leading Tecfidera (dimethyl glutamate) and new injectables like Roche’s Ocrevus(ocrelizumab) also making strong headway in the market. ... There is also a looming threat of generic competition to Gilenya and Tecfidera, which could make it harder

Merck takes evobrutinib for MS into phase 3, on mixed data

Merck takes evobrutinib for MS into phase 3, on mixed data If successful, Merck will have a chance to bring forward a new-mechanism therapy for relapsing MS that will compete with blockbuster oral drugs such as Biogen’s Tecfidera (dimethyl fumarate), ... It will also have to contend with newer drugs like

Tecfidera successor’s side-effect profile boosts Biogen

Tecfidera successor’s side-effect profile boosts Biogen One of the biggest issues is that these newer treatments don’t cause the gastrointestinal side-effects frequently seen in patients taking Tecfidera. ... Overall discontinuation rates were 1.6% for Vumerity and 6.0% for Tecfidera.

Biogen grows in Q2, but Spinraza performance a concern

Biogen grows in Q2, but Spinraza performance a concern The performance was thanks largely to its under-pressure multiple sclerosis (MS) franchise, where combined sales of Tecfidera, Avonex, Plegridy and Tysabri totalled $2.2bn. ... palsy. One big binary decision awaiting the firm is a challenge

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