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PMLiVE Top Pharma List

Zetia

The Top Pharma List's top 50 pharmaceutical products by global sales ranking is compiled from GlobalData's pharmaceutical revenue figures. Zetia was produced by Merck & Co. and Bayer.

TMC rockets on data for twice-yearly cholesterol drug inclisiran

TMC rockets on data for twice-yearly cholesterol drug inclisiran

control the LDL-cholesterol levels despite maximum doses of statin drugs, with or without Merck &Co’s add-on therapy Zetia (ezetimibe).

Esperion craters as deaths mar atherosclerosis drug study

Esperion craters as deaths mar atherosclerosis drug study earlier phase III trial and the company has reiterated its plans to file for approval as a monotherapy and in combination with Merck &Co/MSD’s Zetia (ezetimibe) in the US

CETP inhibitor class finally dies as Merck abandons anacetrapib

CETP inhibitor class finally dies as Merck abandons anacetrapib Some have argued that the company should file given its big investment in the project and established commercial infrastructure, which succeeded in turning another cholesterol-lowering drug with lacklustre data - Zetia

Merck & Co's anacetrapib data fails to generate much excitement

Merck & Co's anacetrapib data fails to generate much excitement selling Zetia (ezetimibe) and Vytorin (ezetimibe/simvastatin) in this therapeutic area despite a small effect on cardiovascular outcomes.

First round to Amgen in PCSK9 patent battle with Sanofi

First round to Amgen in PCSK9 patent battle with Sanofi For example, some payers are insisting that patients on statins try adding Merck &Co's selective cholesterol-absorption inhibitor Zetia (ezetimibe) before moving on to a PCSK9 inhibitor.

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