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PMLiVE Top Pharma List

Zetia

The Top Pharma List's top 50 pharmaceutical products by global sales ranking is compiled from GlobalData's pharmaceutical revenue figures. Zetia was produced by Merck & Co. and Bayer.

NICE backs Repatha but rejects cholesterol rival Praluent

NICE backs Repatha but rejects cholesterol rival Praluent Specifically, the UK watchdog said it was concerned that unlike Repatha Praluent has not been compared to the existing combination therapy of a statin plus MSD's Zetia (ezetimibe) in clinical

FDA panel rejects cardiovascular outcomes claim for Vytorin

FDA panel rejects cardiovascular outcomes claim for Vytorin It found a modest benefit with the addition of CETP inhibitor ezetimibe (Merck's Zetia) to the statin; 32.7% of the combination group suffered a major cardiovascular event over a ... Regardless of the outcome of the FDA's deliberations, Merck will face

PCSK9 inhibitors vastly over-priced, says ICER report

PCSK9 inhibitors vastly over-priced, says ICER report ICER's recommended price level would put Repatha and Praluent roughly in line with the price of Merck &Co's rival cholesterol drug Zetia (ezetimibe), which has been shown to be

Merck hopes for another Keytruda with new immunotherapy deal

Merck hopes for another Keytruda with new immunotherapy deal But Merck has been hit by the on-going erosion to its cardiovascular and cholesterol drugs Zetia (ezetimibe) and Vytorin (ezetimibe/simvastatin). ... This is primarily due to loss of exclusivity of Zetia in Canada and declines of both products in the US.

Relief as study finds no cardiovascular risk with Januvia

Relief as study finds no cardiovascular risk with Januvia Overall pharma sales fell 2% on the back of declines for cholesterol drugs Zetia (ezetimibe) and Vytorin (ezetimibe/simvastatin) as well as immunotherapeutic Remicade (infliximab) which is facing biosimilar competition in

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