1. Clearly define the issue/ opportunity you wish to address
2. Understand the regulatory environment
3. Carry out business modelling
4. Establish what's really in it for the patient
5. Remeber who you are talking to
6. Segment in a practical manner
7. Defining where your audience is in the treatment lifecycle
8. Ensure consistency with other stakeholder activities
9. Fully integrate your public relations
10. Measure what is important
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