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Pfizer and Arvinas announce $1bn deal for investigational oral protein degrader

ARV-471 is currently in a phase 2 trial for the treatment of patients ER-positive, HER2-negative locally advanced or metastatic breast cancer

Roche engaged in talks with FDA for Alzheimer’s drug candidate

CEO Severin Schwan told reporters Roche will complete a phase 3 trial of gantenerumab in the second half of 2022

One dose of AZ’s COVID-19 vaccine ‘highly effective’ against severe disease from variants

New real-world data from Canada shows vaccine efficacy was lower against milder symptomatic disease with one dose

J&J, distributors reach $26bn settlement to address the opioid crisis in the US

The proposed agreement would resolve claims of both states and local governments in the US

Novartis sees demand returning to pre-COVID-19 levels in Q2 results

Swiss pharma company also provided key updates on a number of drug candidates in its pipeline

Merck, Eisai’s Keytruda/Lenvima regimen scores full approval in endometrial cancer

Keytruda plus Lenvima was previously approved under the FDA’s accelerated approval process

EU approves bluebird bio’s CALD gene therapy Skysona

CALD is a progressive and fatal neurodegenerative disease that overwhelmingly affects males

NHS earmarks £340m for new medicines fund to fast-track ‘innovative’ treatments

The proposed Innovative Medicines Fund is an extension of the existing Cancer Drugs Fund

EMA begins rolling review of Sanofi, GSK’s COVID-19 vaccine

Rolling review launched based on preliminary results from lab studies and early clinical studies

Q&A: Claire Gillis

PME interviews VMLY&Rx's CEO

Q&A: Sarah Gordon

PME interviews Virgo Health's head of health
Q&A: Amar Urhekar

PME interviews Ashfield Health's Global President

AZ licenses pneumonia mAb to Aridis Pharmaceuticals for $11m upfront

The candidate – suvratoxumab – is ready for phase 3 clinical evaluation for the prevention of pneumonia
Bayer’s BlueRock Therapeutics gains FDA fast track for Parkinson’s disease cell therapy

In 2019, Bayer bought out its private equity partner Versant Ventures and founders in BlueRock Therapeutics for $240m
BioNTech plans acquisition of Kite’s TCR cell therapy R&D platform

German biotech company said the acquisition will boost its presence in the US
GSK reveals plans for £400m R&D facility expansion in England

GSK has formally started the process of seeking a development partner for the expansion plans
Keytruda scores a win in treating early-stage breast cancer pre- and post-surgery

The FDA had previously rejected a supplemental biologics licence application in this indication
FDA advisory committee votes against approval of AZ, FibroGen's roxadustat

Briefing documents published earlier this week raised questions over the safety profile of roxadustat
Lilly and Banner Alzheimer’s Institute collaborate on donanemab prevention trial

Trial will evaluate donanemab in participants at risk for cognitive and functional decline related to Alzheimer’s

Latest appointments

Langland promotes Jake Davis to managing partner

Davis joined Langland in 2020 as business unit director of the agency’s PR and policy division
Ogilvy Health appoints Rebecca Carter to newly created head of social media role

Three new hires have also joined the dedicated healthcare communications team
Ashfield Health announces three new senior hires

Agustin Ramirez, Beverly Pisarczyk and Kory Koske take on various roles across the business
Fishawack Health restructures creative team

Agency has united its creative capabilities under one team, jointly led by Lacey Jae Christman and Damien Parsonage
Mark Caulfield departs from Genomics England to take on CEO role at Barts Life Sciences

Caulfield served as chief scientist at Genomics England, working on the 100,000 Genomes Project

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