Please login to the form below

Not currently logged in
Email:
Password:

Versiti launches test for vaccine-related blood clot issues

Launch follows reports of very rare blood clots connected to J&J's vaccine

Versiti has launched antibody tests for suspected vaccine-related blood clot issues – thrombotic-thrombocytopenia (VITT) – in the US, amid concerns over a small number of blood clot cases related to AstraZeneca and J&J's COVID-19 vaccines.

Recently, cases of individuals developing blood clots with low platelet counts have been observed connected to Johnson & Johnson’s COVID-19 vaccine.

Before that, similar cases of very rare ‘unusual’ blood clots had been reported in a small number of AstraZeneca/Oxford University vaccine recipients.

Global regulators have since maintained that the vaccines benefits outweigh their risks, although warnings have been issued regarding the possibility of developing such blood clots.

In its review, the European Medicines Agency (EMA) said that a ‘plausible’ explanation for the combination of blood clots and low blood platelets related to AstraZeneca and J&J's COVID-19 vaccines could be due to an immune response.

This immune response leads to a condition that is similar to heparin-induced thrombocytopenia (HIT) that can be seen in patients treated with the anticoagulant heparin.

Versiti’s tests determine the presence of platelet-activating antibodies in the blood – the presence of these antibodies is believed to be a ‘key’ finding following the blood clot cases related to AstraZeneca and J&J's COVID-19 vaccines.

These antibodies, says Versiti, are similar to those seen in HIT – when a patient has these antibodies, alternate anticoagulation therapies must be implemented.

"Accurate assessment of VITT is critical to guiding appropriate drug selection and management of patients with blood clot side effects," said Ruchika Sharma, associate medical director, platelet immunology laboratory at Verstiti.

"Patients receiving incorrect therapies could be at risk for serious bleeding complications or, in some cases, worsening of their existing blood clot(s). This testing menu leverages Versiti's decades of experience in immune platelet disorders, to provide physicians with the necessary tools to aid in the care and management of patients with suspected VITT,” she added.

"For more than 40 years, Versiti has been tirelessly researching cellular and molecular abnormalities in blood-related conditions including immune platelet disorders and HIT," added Brian Curtis, senior laboratory director, platelet immunology laboratory at Versiti.

"Versiti's long and proud history of scientific discovery in blood clotting puts us in a unique position to best aid physicians as they care for patients with suspected VITT."

Article by
Lucy Parsons

29th April 2021

From: Healthcare

Share

Tags

COVID-19 Updates and Daily News

Featured jobs

PMHub

Add my company
Spirit

We find the soul in the science, the humanity in the data, harnessing the power of creativity to deliver medical...

Latest intelligence

JulAug cover image
The Chronicles of Pharma: a creative review of pharma’s journey to omnichannel
Chris Ross conducts a literary-inspired review of pharma’s pursuit of communications excellence...
The key to psoriasis innovation? Dispelling the shadow of the JAK inhibitor
Powerful therapies that can improve skin clarity dominate the psoriasis landscape, so why are most patients stuck in a cycle of ineffective topicals? Fishawack Health explores the market and reveals...
Virtual Speaker Program: A Customer Story
Learn how we helped our client develop a virtual speaker program and roll out a series of regional peer-to-peer education sessions....