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acalabrutinib
This page shows the latest acalabrutinib news and features for those working in and with pharma, biotech and healthcare.
AZ’s BTK inhibitor Calquence fails in COVID-19 study
The CALAVI phase 2 trials had been evaluating the efficacy and safety of Calquence (acalabrutinib) alongside best supportive care (BCS) in patients hospitalised with respiratory complications of COVID-19.
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AZ strengthens Daiichi Sankyo partnership with new ADC deal
acalabrutinib) and its recently approved, Daiichi-partnered HER2-targeting ADC, Enhertu (trastuzumab deruxtecan).
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GSK’s anti-BCMA drug leads crowded CHMP recommendations
AstraZeneca also received two positive opinions following the meeting, with a recommendation for Calquence (acalabrutinib) to treat chronic lymphocytic leukaemia and a label extension of its PD-1 inhibitor Imfinzi (durvalumab)
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AZ revenues rise, but it says coronavirus could hit 2020
Recently-approved for a new chronic lymphocytic leukaemia (CLL) indication, AZ’s rival to Johnson &Johnson’s blockbuster BTK inhibitor Imbruvica (ibrutinib) – Calquence (acalabrutinib) – also gathered momentum and contributed $56m in
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EMA begins review of Kite’s CAR-T for mantle cell lymphoma
Current treatment options for MCL include AstraZeneca’s BTK inhibitor Calquence (acalabrutinib) and Johnson &Johnson/AbbVie’s BTK inhibitor Imbruvica (ibrutinib).
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Merck buys ArQule for $2.7bn in another cancer bolt-on deal
ARQ 531 is in the same general class as Johnson &Johnson’s Imbruvica (ibrutinib) and AstraZeneca’s Calquence (acalabrutinib), but is a reversible, non-covalent inhibitor that zeroes in on a
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