This page shows the latest adaptive trial design news and features for those working in and with pharma, biotech and healthcare.
There were also some associated safety signals in clinical laboratory findings of the add-on Discovery trial associated with each drug. ... That included taking a look at the use of global, multi country, adaptive trial design with a common data safety
The experts noted that while a conventional randomised controlled trial would be the preferred option, it may be possible to consider alternative designs such as the "randomised stepped wedge" model. ... This is an adaptive trial design that draws on
The pharma industry is slowly starting to embrace adaptive trial design, though not as quickly as once hoped, thanks largely to regulatory uncertainty. ... A survey carried out byhas found that while many drug companies are anticipating the use of an
Berry is one of the principal investigators in a new trial which arguably takes the adaptive trial design concept to a new height. ... Berry hopes I-SPY 2 will serve as a showcase for the power of adaptive trial design, and continue to encourage the
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For example, an adaptive design empowers trial leads to decide during the process to focus on a subpopulation – maybe a certain type of biomarker or a particular demographic. ... Recent health economic analysis evaluating the savings associated with
competitive data, trial recruitment problems, and trial design that is ill-suited to making rapid progress against this elusive disease. ... The EPAD platform will allow new therapies to be tested in a streamlined way, using adaptive trial design to test
There has been a rapid evolution in clinical trial design in IO, eg basket trials, adaptive trials, etc. ... CL: Evolution of trial design has benefited greatly in past decades, as the search for meaningful signals in patients has provided faster
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From new methodology to IND submission priority to portfolio impact, adaptive trial design continues to make headway in the US and Europe. ... Adaptive trial design continues to make headway with both the FDA and EMA recognising the benefits that this
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