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ALS
This page shows the latest ALS news and features for those working in and with pharma, biotech and healthcare.
Latest news
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Biogen and Alcyone Therapeutics partner in deal worth over $50m
In exchange, Biogen will receive an exclusive global licence to ThecaFlex in spinal muscular atrophy (SMA) and amyotrophic lateral sclerosis (ALS), as well as a co-exclusive global licence in an
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Verge Genomics begins human trials with AI-sourced ALS drug
evaluating VRG50635, a small molecule inhibitor of PIKfyve, as a treatment of amyotrophic lateral sclerosis (ALS), also known as motor neurone disease. ... subjects – phase 1a – and multiple-dose study in patients with ALS – phase 1b.
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FDA awards over $38m for advancement of rare disease treatments
In line with the FDA Rare Neurodegenerative Disease Grant Program, which was recently established specifically for ALS and other rare neurodegenerative diseases, three of the natural history studies awarded by the ... One contract, co-funded by the
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WHO unveils AI-powered digital health worker, Florence 2.0
lifestyle choices,” said Dr Yousuf Al Maslamani, official healthcare spokesperson for the FIFA World Cup Qatar 2022, Ministry of Public Health.
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Amylyx’s Relyvrio receives FDA approval for ALS treatment
Relyvrio was shown to significantly slow physical decline in people living with ALS. ... Joshua Cohen and Justin Klee, co-chief executive officers of Amylyx said the approval was “an exciting milestone for the ALS community”.
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Latest Intelligence
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Rare disease drug development – real-world evidence innovations with historical controls
Patel et al have recently conducted an analysis of international HTA submissions from 2011- 2019 to determine the acceptability of single arm clinical studies and ECs as part of the drug
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How diversity and inclusion continues to be incorporated in dermatology
5 Augustin M, Alvaro-Gracia JM, et al. A framework for improving the quality of care for people with psoriasis. ... British Journal of Dermatology 2007; 156(6): p1245–50. 9 Mustonen A, et al.
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Looking to the future of patient empowerment
As part of our literature research into lupus, a review by Dantas et al.
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Should we stop talking about people as patients and start thinking of them as partners? After all, it is their physical and mental health and well-being
In 2021, an academic review of 20 lupus apps demonstrated that current mHealth tools available to this patient population are of poor quality and limited functionality (Dantas et al, 2020).
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AI and genomics: a revolution in drug discovery and development
We can also generate new findings from old data sets. For example, we looked at genetic data from patients with ALS. ... Using our approach we quickly identified and validated with multiple KOLs 33 additional genes that were strongly associated with
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Approximately 0 fully matching, plus 24 partially matching documents found.
Latest appointments
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Flex Pharma appoints new R&D president
With their successful partnership from their time at Sepracor, Bill and our CMO, Dr Tom Wessel, are a great team to rapidly advance our phase II clinical trials in MS, ALS ... and Charcot-Marie-Tooth with FLX-787 which will be amongst the most advanced
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Nobel laureate Dr Walter Gilbert joins Amylyx Pharmaceuticals
The US-based pharmaceutical firm specialises in developing disease-modifying treatments for neurodegenerative diseases, including Amyotrophic Lateral Sclerosis (ALS). ... Loeb University Professor Emeritus at Harvard University. He said: “Amylyx has
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Boyds appoints Dr Nick Meyers and Natasha Nesterova-Smith
Having worked in the industry for over 20 years, Dr Meyers also brings experience from Phytopharm, where he worked on the treatment of Parkinson's disease and ALS, and Alizyme Therapeutics,
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M3 Europe appoints Helen Parfitt and Grant Irwin
Prior to this he served at companies including Agnitio and IMS Health, in the process working with al of the top 20 life science companies on both a regional and global
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Biogen's Douglas Williams departs for biotech start-up
We are fortunate to have Al Sandrock and Spyros Artavanis-Tsakonas to lead the work to which Biogen is dedicated.”.
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Latest from PMHub
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WHY ARE PATIENT SUPPORT PROGRAMMES NOT WORKING?
productive conversations with their doctor (e.g., Adams, 2010; Riggare et al., 2019). ... Interestingly, all these outcomes are addressed when patients enrol in a PSP (Ganguli et al., 2016).
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Could femtech be the answer to the gender health gap?
Accessed October 27, 2021. Hagen S, Elders A, Stratton S, et al. ... Published October 9, 2001. Accessed October 27, 2021. Ugalmugle S, et al.
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End-to-end patient strategy: Making a treatment for patients, with patients
Clinical Pharmacology &Therapuetics. 2019; 105(3):672-683. Tsai JH et al. MDM Policy &Practice. ... 2021; 6(2). doi:10.1177/23814683211039457. Cavaller-Bellaubi, M et al. Therapeutic Innovation &Regulatory Science.
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Actionable Insights for Medical Affairs: Elusive or Within Reach?
Dash S, Shakyawar S, Sharma M, et al. Big data in healthcare; management, analysis and future prospects.
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Precision versus personalised medicine
ESMO Daily Reporter. CAR-T-cell therapy. Available at: . Accessed November 2022. Qin VM, et al. Cancers (Basel).2021; 13:404. Petersen BS, et al. ... BMC Genet. 2017; 18:14. Panell M, et al. JCO Precis Oncol.
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Approximately 3 fully matching, plus 64 partially matching documents found.
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- Roche and Eli Lilly to collaborate on Alzheimer’s disease blood test
- Novo Nordisk suspended from ABPI over ‘serious’ code of practice breaches
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