This page shows the latest bezlotoxumab news and features for those working in and with pharma, biotech and healthcare.
Other emerging strategies for the prevention of C. diff recurrence include antibodies like Merck &Co's recently-approved Zinplava (bezlotoxumab) – which works by neutralising toxins secreted by the bacterium – and prophylactic
Meanwhile, other emerging strategies for the prevention of C. diff recurrence include antibodies like Merck &Co's recently-approved Zinplava (bezlotoxumab) - which works by neutralising toxins secreted by the bacterium - and
2020. A marketing authorisation application for bezlotoxumab has been filed with the EMA and is also under review. ... Bezlotoxumab was originally developed by Medarex, which was acquired by Bristol-Myers Squibb in 2009.
Another antibody being developed as a combination with bezlotoxumab, actoxumab, was dropped from the study for "efficacy and safety reasons" after an interim analysis, according to Merck. ... Bezlotoxumab and actoxumab were developed in house by Merck in
Actoxumab/bezlotoxumab (MK-3415A) is a combination of two antibodies in phase III development to prevent recurrence of the serious infection Clostridium difficile.
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