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CAR T-cell therapy

This page shows the latest CAR T-cell therapy news and features for those working in and with pharma, biotech and healthcare.

Kite reports positive three-year results for CAR T-cell therapy in rare blood cancer

Kite reports positive three-year results for CAR T-cell therapy in rare blood cancer

Kite, a Gilead company, has reported positive three-year follow-up results from an ongoing study of its CAR T-cell therapy Tecartus (brexucabtagene autoleucel) in relapsed/refractory B-cell acute ... The positive results come just days after the company

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  • CAR-T cell therapy in oncology CAR-T cell therapy in oncology

    Next generation CAR-T cell therapy. First generation, autologous CAR-T cell immunotherapies have demonstrated significant clinical promise. ... However, it is well recognised that the full potential of CAR-T cell therapy has yet to be fully exploited.

  • Think fast, be different: succeeding at speed chess in 2021’s COVID-19 world Think fast, be different: succeeding at speed chess in 2021’s COVID-19 world

    EBCs also demonstrate positive data and are bringing novel therapies to market in complex areas of medicine, including gene therapy, CAR T-cell therapy and rare diseases. ... These visuals got the message across in an engaging, novel and efficient manner

  • Surviving cancer: a new era for patients Surviving cancer: a new era for patients

    Chimeric antigen receptor T-cell therapy. Chimeric antigen receptor (CAR) T-cell therapy consists of engineering receptors in the body that selectively interact with cancer cells, inducing cell death without affecting ... CAR-T therapy has potential

  • Cell and gene therapy Cell and gene therapy

    In addition, as Eric Althoff from Swiss pharmaceutical firm Novartis points out, making a patient-specific product like a CAR-T therapy is very different from producing a volume drug. ... We estimate the cost [of making a CAR-T cell therapy for a single

  • Drug launches to watch in 2019 Drug launches to watch in 2019

    1. Zolgensma – the $4m per patient gene therapy. The first CAR-T cell therapies, Novartis’ Kymriah and Gilead/Kite’s Yescarta, were launched in Europe in 2018, while Spark’s gene ... The analysts predict the drug will be priced at around $550,

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  • Precision versus personalised medicine Precision versus personalised medicine

    Targeted therapy’ is a broad term that often refers to the use of drugs that target specific proteins, cell surface molecules, or genes. ... ESMO Daily Reporter. CAR-T-cell therapy. Available at: . Accessed November 2022. Qin VM, et al. Cancers

  • Understanding the evolving CAR-T market

    In August 2017, Novartis made history after receiving FDA approval for Kymriah, the world’s first chimeric antigen receptor T-cell (CAR-T) therapy. ... Today, the CAR-T market is expected to increase at an annual rate of 30% until 2030.

  • Precision paediatrics: Treating patients with CAR-T

    He is part of a team using a groundbreaking chimeric antigen receptor T-cell (CAR-T) therapy, which is transforming outcomes for children who would otherwise have no treatment options left. ... SA: CAR-T cell therapy is an innovative immunotherapy that

  • Highlights in haematologic malignancy from ASH 2018

    The spotlight shone on Chimeric Antigen Receptor(CAR) T-cell therapy; a transformative approach where the patient’s T cells are harvested and re-engineered to recognise antigens expressed by the ... A reduced risk of relapse was also seen when

  • Innovation in pharma: the highs and lows of the current healthcare economy

    Also in cancers: chimeric antigen receptor T cell (CAR-T) therapy, a type of cancer immunology that could dismiss chemotherapy in some cancers, is now licensed in the US. ... The approach is to deliver treatments which restore or establish normal cell

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