This page shows the latest CAR T-cell therapy news and features for those working in and with pharma, biotech and healthcare.
Kite, a Gilead company, has reported positive three-year follow-up results from an ongoing study of its CAR T-cell therapy Tecartus (brexucabtagene autoleucel) in relapsed/refractory B-cell acute ... The positive results come just days after the company
Bristol Myers Squibb (BMS) and 2seventy bio – a spin-out of bluebird bio – have announced positive results from a phase 3 trial of their CAR-T cell therapy Abecma (idecabtagene vicleucel) ... According to the companies, this marks the first time a CAR
Yescarta is the first CAR T-cell therapy recommended for routine use on the NHS. ... will ensure that patients needing third-line treatment will continue to have access to CAR T-cell therapy.
BioNTech’s oncology portfolio includes 19 candidates across a total of 24 clinical trials, including its novel CAR-T cell therapy candidate BNT211, which the company announced in September had demonstrated
refractory (R/R) diffuse large B-cell lymphoma (DLBCL) after two or more lines of systemic therapy. ... Additionally, patients naïve to treatment with chimeric antigen receptor (CAR) T-cell therapy achieved 69% ORR and 42% CR and patients previously
First-generation autologous CAR T-cell therapies have dramatically changed outcomes for people with certain blood cancers yet more work needs to be done to reach additional patients. ... As the global CAR T-cell therapy leader, Kite is working on the
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Next generation CAR-T cell therapy. First generation, autologous CAR-T cell immunotherapies have demonstrated significant clinical promise. ... However, it is well recognised that the full potential of CAR-T cell therapy has yet to be fully exploited.
EBCs also demonstrate positive data and are bringing novel therapies to market in complex areas of medicine, including gene therapy, CAR T-cell therapy and rare diseases. ... These visuals got the message across in an engaging, novel and efficient manner
Chimeric antigen receptor T-cell therapy. Chimeric antigen receptor (CAR) T-cell therapy consists of engineering receptors in the body that selectively interact with cancer cells, inducing cell death without affecting ... CAR-T therapy has potential
In addition, as Eric Althoff from Swiss pharmaceutical firm Novartis points out, making a patient-specific product like a CAR-T therapy is very different from producing a volume drug. ... We estimate the cost [of making a CAR-T cell therapy for a single
1. Zolgensma – the $4m per patient gene therapy. The first CAR-T cell therapies, Novartis’ Kymriah and Gilead/Kite’s Yescarta, were launched in Europe in 2018, while Spark’s gene ... The analysts predict the drug will be priced at around $550,
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Ceylad appoints new CFO. Clinical-stage biopharma focused on the development of CAR-T cell therapies has announced that Filippo Petti has been appointed as Chief Financial Officer. ... He said: “Celyad’s differentiated approach to the field of CAR-T
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Targeted therapy’ is a broad term that often refers to the use of drugs that target specific proteins, cell surface molecules, or genes. ... ESMO Daily Reporter. CAR-T-cell therapy. Available at: . Accessed November 2022. Qin VM, et al. Cancers
In August 2017, Novartis made history after receiving FDA approval for Kymriah, the world’s first chimeric antigen receptor T-cell (CAR-T) therapy. ... Today, the CAR-T market is expected to increase at an annual rate of 30% until 2030.
He is part of a team using a groundbreaking chimeric antigen receptor T-cell (CAR-T) therapy, which is transforming outcomes for children who would otherwise have no treatment options left. ... SA: CAR-T cell therapy is an innovative immunotherapy that
The spotlight shone on Chimeric Antigen Receptor(CAR) T-cell therapy; a transformative approach where the patient’s T cells are harvested and re-engineered to recognise antigens expressed by the ... A reduced risk of relapse was also seen when
Also in cancers: chimeric antigen receptor T cell (CAR-T) therapy, a type of cancer immunology that could dismiss chemotherapy in some cancers, is now licensed in the US. ... The approach is to deliver treatments which restore or establish normal cell
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